ID   A0A0F4RI57_9RHOB        Unreviewed;       734 AA.
AC   A0A0F4RI57;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   RecName: Full=Peptidase M10 serralysin C-terminal domain-containing protein {ECO:0000259|Pfam:PF08548};
GN   ORFNames=TW80_10740 {ECO:0000313|EMBL:KJZ19260.1};
OS   Loktanella sp. S4079.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Loktanella.
OX   NCBI_TaxID=579483 {ECO:0000313|EMBL:KJZ19260.1, ECO:0000313|Proteomes:UP000033741};
RN   [1] {ECO:0000313|EMBL:KJZ19260.1, ECO:0000313|Proteomes:UP000033741}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S4079 {ECO:0000313|EMBL:KJZ19260.1,
RC   ECO:0000313|Proteomes:UP000033741};
RX   PubMed=25879706; DOI=10.1186/s12864-015-1365-z;
RA   Machado H., Sonnenschein E.C., Melchiorsen J., Gram L.;
RT   "Genome mining reveals unlocked bioactive potential of marine Gram-negative
RT   bacteria.";
RL   BMC Genomics 16:158-158(2015).
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KJZ19260.1}.
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DR   EMBL; JXYE01000003; KJZ19260.1; -; Genomic_DNA.
DR   RefSeq; WP_045997400.1; NZ_JXYE01000003.1.
DR   AlphaFoldDB; A0A0F4RI57; -.
DR   STRING; 579483.TW80_10740; -.
DR   PATRIC; fig|579483.3.peg.2205; -.
DR   OrthoDB; 9342475at2; -.
DR   Proteomes; UP000033741; Unassembled WGS sequence.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.150.10.10; Serralysin-like metalloprotease, C-terminal; 3.
DR   InterPro; IPR018511; Hemolysin-typ_Ca-bd_CS.
DR   InterPro; IPR001343; Hemolysn_Ca-bd.
DR   InterPro; IPR013858; Peptidase_M10B_C.
DR   InterPro; IPR003995; RTX_toxin_determinant-A.
DR   InterPro; IPR011049; Serralysin-like_metalloprot_C.
DR   PANTHER; PTHR38340; S-LAYER PROTEIN; 1.
DR   PANTHER; PTHR38340:SF1; S-LAYER PROTEIN; 1.
DR   Pfam; PF00353; HemolysinCabind; 4.
DR   Pfam; PF08548; Peptidase_M10_C; 1.
DR   PRINTS; PR00313; CABNDNGRPT.
DR   PRINTS; PR01488; RTXTOXINA.
DR   SUPFAM; SSF51120; beta-Roll; 2.
DR   PROSITE; PS00330; HEMOLYSIN_CALCIUM; 4.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000033741};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Toxin {ECO:0000256|ARBA:ARBA00022656};
KW   Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT   DOMAIN          401..464
FT                   /note="Peptidase M10 serralysin C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08548"
FT   REGION          499..531
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        511..525
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   734 AA;  75813 MW;  C607B86AA5863246 CRC64;
     MSEITLVTYL SAGEPFAYSH IAELSLVSVN GTDFLYSTTE YDGVLVGWNI SGTVPVMIDS
     YTYDGVALAG VSPSLCVITF GGVTSLLSGG AENGQLQLIS LNPDGTFYHT SDLPVTGLHN
     YTAMTLGDGT SVVISGVANG DGIARILFDS TGGYIGDQNS KPAGAFTDHI AATEVIEISG
     NQYAITASQT DAGITSWEID VSGNLLPRAS IGPDQNLWID TPTVMQSVEI DGKAYVIVGA
     SGSGSLTVLQ LLPDGTFEIR DHILDTLDTR FNGIAALDVV EHHGQTYVIA GGSDDGISIF
     LLMEDGTLLP RAHIADSPAM GLDNVSDIVG LRTESGIELY VSSSSEQGLT KLRYETAQIG
     LAVTAEVAGS NLNGTAAADV LIGLAGDDTL IGGDGADILR DGSGSDLLTG GAGADVFVLS
     ADGADDTITD FTIGEDVIDL SRWSMLRDVS QLTMRITADG AEIIYGDERL ILHSSDGLPI
     DYRQFTNSDL IAVTRIPQDV TSGYPGPAIP NPDTGTEPPP ADDPSRRNPL SSVTTIASDN
     FSTIVEAIGD DVIAPPGTPG AVIVGNTTLN GSASADVLIG GTTNDLMNGA DGDDTLLGRD
     GNDHLNGDAG ADLLIGGAGD DQLDGGTGQD ILRGGEGADT LHGGAGNDIL FGDAGADTFI
     FDGGTDVIAD FAQGDDHITL SETLWTGLTS VDDLILIYGT YTGTTMTISF DDDNILVIEN
     VTDPSILSDD ITLF
//