ID   A0A0F4YK45_TALEM        Unreviewed;       634 AA.
AC   A0A0F4YK45;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=Rho GTPase activator (Rgd1) {ECO:0008006|Google:ProtNLM};
GN   ORFNames=T310_7537 {ECO:0000313|EMBL:KKA18500.1};
OS   Rasamsonia emersonii CBS 393.64.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Rasamsonia.
OX   NCBI_TaxID=1408163 {ECO:0000313|EMBL:KKA18500.1, ECO:0000313|Proteomes:UP000053958};
RN   [1] {ECO:0000313|EMBL:KKA18500.1, ECO:0000313|Proteomes:UP000053958}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 393.64 {ECO:0000313|EMBL:KKA18500.1,
RC   ECO:0000313|Proteomes:UP000053958};
RA   Heijne W.H., Fedorova N.D., Nierman W.C., Vollebregt A.W., Zhao Z., Wu L.,
RA   Kumar M., Stam H., van den Berg M.A., Pel H.J.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKA18500.1}.
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DR   EMBL; LASV01000448; KKA18500.1; -; Genomic_DNA.
DR   RefSeq; XP_013325112.1; XM_013469658.1.
DR   AlphaFoldDB; A0A0F4YK45; -.
DR   STRING; 1408163.A0A0F4YK45; -.
DR   GeneID; 25319809; -.
DR   OrthoDB; 5482027at2759; -.
DR   Proteomes; UP000053958; Unassembled WGS sequence.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd07652; F-BAR_Rgd1; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR031160; F_BAR.
DR   InterPro; IPR001060; FCH_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR23176:SF138; RHO GTPASE ACTIVATOR; 1.
DR   PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR   Pfam; PF00611; FCH; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS51741; F_BAR; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053958}.
FT   DOMAIN          30..297
FT                   /note="F-BAR"
FT                   /evidence="ECO:0000259|PROSITE:PS51741"
FT   DOMAIN          441..631
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          1..52
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          81..102
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          321..433
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..40
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        335..389
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        396..411
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        412..429
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   634 AA;  69792 MW;  A2C053D417618AAB CRC64;
     MAEVASSDAQ LPPALPSQDD SASPAGVRPQ SSSGQNTGPE TAAADPDKER IDRVLQSEDF
     ATFLKKRAAL EEEHAQGLKK LARLSQETTH RSDHRQGTYS RAQDEVNRIQ ERMADHGLQF
     AVSLQQMSED LQELASNIER GRKQWKQTGL NAEKKVQDAE SQVEKAKAKY DSLAEQYDRV
     RTGDKQSGKF GLKGHKSAAQ HEEDLHRKVQ NADSDYQAKV QAAQTARQEL VSTHRPQTVH
     HLQRLIYECD SGLTLQLQKF AAFNEKLLLG QGLCVSPLNS GSKSMREVIH QIDSEKDFND
     YILSFAGNPG AVAAPEVQYT PHPTLAPASA PSAPPSQPNT QNKRQSLALH AAMPSQQSLG
     PTSPPQTSPQ AGQGSTLPPS FSPQPSSEGY QAYHPPYPTD PTPPPLQQPV SSGPPMGRSP
     VLQPTNGYQP NLPPLNPVFG VSLEELYRRD GSAVPMIVYQ CIQAVELFGL DVEGIYRLSG
     SANHINHMKA LFDNDSSQVD FTNPESFYHD VNSVAGLLKQ FFRELPDPLF TRQYYQDFIN
     AARIDNDVQR RDTLHAIINN LPDPNYATLC ALVLHLNKVQ EHYPQNRMNA GNLAICFGPT
     LMGANSGGNI ADAGWQARVI ETVLLNTFQI FDDD
//