ID   A0A0F4Z4J7_TALEM        Unreviewed;      1067 AA.
AC   A0A0F4Z4J7;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Fumarylacetoacetate hydrolase {ECO:0000313|EMBL:KKA25245.1};
GN   ORFNames=T310_0741 {ECO:0000313|EMBL:KKA25245.1};
OS   Rasamsonia emersonii CBS 393.64.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Rasamsonia.
OX   NCBI_TaxID=1408163 {ECO:0000313|EMBL:KKA25245.1, ECO:0000313|Proteomes:UP000053958};
RN   [1] {ECO:0000313|EMBL:KKA25245.1, ECO:0000313|Proteomes:UP000053958}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 393.64 {ECO:0000313|EMBL:KKA25245.1,
RC   ECO:0000313|Proteomes:UP000053958};
RA   Heijne W.H., Fedorova N.D., Nierman W.C., Vollebregt A.W., Zhao Z., Wu L.,
RA   Kumar M., Stam H., van den Berg M.A., Pel H.J.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the FAH family. {ECO:0000256|ARBA:ARBA00010211}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKA25245.1}.
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DR   EMBL; LASV01000030; KKA25245.1; -; Genomic_DNA.
DR   RefSeq; XP_013331857.1; XM_013476403.1.
DR   AlphaFoldDB; A0A0F4Z4J7; -.
DR   STRING; 1408163.A0A0F4Z4J7; -.
DR   GeneID; 25312795; -.
DR   OrthoDB; 1430490at2759; -.
DR   Proteomes; UP000053958; Unassembled WGS sequence.
DR   GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd01299; Met_dep_hydrolase_A; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 3.90.850.10; Fumarylacetoacetase-like, C-terminal domain; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   Gene3D; 2.30.40.10; Urease, subunit C, domain 1; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR006680; Amidohydro-rel.
DR   InterPro; IPR011234; Fumarylacetoacetase-like_C.
DR   InterPro; IPR036663; Fumarylacetoacetase_C_sf.
DR   InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11820; ACYLPYRUVASE; 1.
DR   PANTHER; PTHR11820:SF115; FUMARYLACETOACETATE HYDROLASE; 1.
DR   Pfam; PF12697; Abhydrolase_6; 1.
DR   Pfam; PF01979; Amidohydro_1; 1.
DR   Pfam; PF01557; FAA_hydrolase; 1.
DR   PRINTS; PR00111; ABHYDROLASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF51338; Composite domain of metallo-dependent hydrolases; 1.
DR   SUPFAM; SSF56529; FAH; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:KKA25245.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053958}.
FT   DOMAIN          118..461
FT                   /note="Amidohydrolase-related"
FT                   /evidence="ECO:0000259|Pfam:PF01979"
FT   DOMAIN          556..767
FT                   /note="Fumarylacetoacetase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01557"
FT   DOMAIN          820..1062
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000259|Pfam:PF12697"
SQ   SEQUENCE   1067 AA;  116180 MW;  330C95C87A3FB2E5 CRC64;
     MAPISTQDIT NGVNGINGHA GGMATWGSRR PTRKLCPHED LRFDPKLMPK KYKIAGTSPD
     SKILFLDVNI IDSTGADPYR GDVYIEGERI RYVGTVPNVN RLQRDPKVKV IRGRGRTLMS
     GLGDAHTHFT WNNGALSNLG EMGVEEHTIL TAKSAQAYLD SGYTMCYGAA SAKDRLDCVI
     RDAINRGDLP GPRYMANGKE MARRNGELEP GITAFADGPL EMREVIRHHV SIGVDQIKLS
     MSGEEILETR SAQDCYFTEE ETAACVDEAH RHGIKVSSHA RSRDSVMQCL KYGVDVIYHA
     SYIDEEGMDL LEKNKHKHVV APGLNWLWAT IYEAGPFGYS FEKAEQVGYK KELEIAIRAL
     KEMHERGITV LPGGDYGFAW TPHGTYARDL EHFVKLLDFT PMEAIIAATA GVASLFDPSE
     LGKIQPGYYA DCILVDGDPL KDISILQDHD KLNVIIINGR IHKASYKEFL SVQPELIPPP
     RQTFTNFVAY ADNLGRPRIG HLDLDQSTIT PLTMASGSPI SNLYEVIELG NEVVPSEETL
     PLNSVQLLPP ISGRDVLAVG KNYPEHATEF NRSGYDSSDK VDQPSHPVIF TKRSTSIIAC
     GEEIYPHPEF TQTLDYEGEI GVIIGKAGYK IDEKDAMDYV WGYTIINDVT ARERQRDHKQ
     FFIGKSADTF CPMGPIAVPA ANLPETLRVQ TFVNGQKRQD GTTKDLIFSV AKLVKTISEG
     ITLQPGDVLA TGTPAGVGFG QDPPTFLKPG DIVEVSVTGL GRLRNRVADA SSANYAAERI
     STVTNLPTYN LEITCGGVGL TQIGDKFINV KKVGNGSEKI VFVHGLGGTT EYWTPLIESA
     GLKDNYTCYV YDLEGHGLTP TKSSSVVTMD TFAEDLAGIF AHANITSDNG GAILVGHSLG
     CLIAMTFAVR NPSLVKKLIL TGPGPSPFPA AASEATYKRA AAVRAHGMLA SGVADAVSNA
     ATSQKTKTSR PVAYAAVRSS LLAQIPEGYA KACTALAGSK DTEIEIEKLT MDTLILTGDE
     DKVSPVDLVK KMKSRMKNAR VEILNDVGHW HIYEDPEGVA RAVKAFL
//