ID A0A0F5JTN1_9BURK Unreviewed; 879 AA.
AC A0A0F5JTN1;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
DE AltName: Full=DNA 3'-5' helicase II {ECO:0000256|ARBA:ARBA00034923};
GN ORFNames=WM40_24635 {ECO:0000313|EMBL:KKB61183.1};
OS Robbsia andropogonis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Robbsia.
OX NCBI_TaxID=28092 {ECO:0000313|EMBL:KKB61183.1, ECO:0000313|Proteomes:UP000033618};
RN [1] {ECO:0000313|EMBL:KKB61183.1, ECO:0000313|Proteomes:UP000033618}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ICMP2807 {ECO:0000313|EMBL:KKB61183.1,
RC ECO:0000313|Proteomes:UP000033618};
RA Lopes-Santos L., Castro D.B., Ottoboni L.M., Park D., Weirc B.S.,
RA Destefano S.A.;
RT "Draft Genome Sequence of Burkholderia andropogonis type strain ICMP2807,
RT isolated from Sorghum bicolor.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKB61183.1}.
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DR EMBL; LAQU01000062; KKB61183.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F5JTN1; -.
DR STRING; 28092.WM40_24635; -.
DR PATRIC; fig|28092.6.peg.5806; -.
DR OrthoDB; 5298826at2; -.
DR Proteomes; UP000033618; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 2.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000033618}.
FT DOMAIN 147..670
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT REGION 80..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 168..175
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 879 AA; 99211 MW; DC5B1C322A238002 CRC64;
MQVLHVCVES GQSKSRALPF EDFARGGPHE FKKQGDFKTR MLQRSVAGSP VLRGLSMMHW
FLQLWANVLA FLGLARTRES KDVTRTPEPV QQSLPMKPQQ PKSAPTSAVV TVKDVYAGDA
FEIKASTQRN AREHMYREKE PGSSKLIGPT DNQLRLIFST RAALPVLAGA GSGKSTSLVN
RFLLATNYLN VQLRHITVFT FTRKSRRDFI EKLIEESQFW PTPITLKEAE ASVRTFHSKA
LQLFRAKRGR DVAVFEFLKD EIPAAKNSAE ATIPTSDVAP PSDDLLSEEE FRANDVDSLM
PGNLSRIQLR LLHDAYTTRF SQSNSFRLVV RELLKASFLS PPIAKDDKDA LEAIRFERQI
LRRDEQWSAY VEADWRRRGL WPLPGVRELN SPDERRPLIA ENGQYAAHGY IASVDTYVVL
GVHSEISNKV NGFGGTTLVK NFQASKNKQA LLLAQCEQKI RYVTDEKDLT ALKKQLHWAA
LPETNVAPKF KIRIPGERKL LPVFYALFTF GQFAENLAVD PCTLDQLHLL AKGSVEEQFG
RACAEYYSSF YEALGARRVW TFNQIFKALA DEQDVLGEMD AADLSPIQHL LIDEFQDISP
AIVKFVTAAQ TRLWKKSGDA IQPTLIAVGD DWQSIYGWRG SSPKFFMDFH KYFRGSPRQA
LQLNQNFRSS ANIIRAAEAA LVDLRERLEG KLNGEAESRY KNLPIPVCQV TEFKSDDVVR
VVRMLLQGKK KGERVFVLSR AKLDATAKAV RDVFRAVSER DLLVTTLHQS KGLEADYVIL
LGEIRYVGRN VLRNSVYLKA ELVGSAHGRE RAYDLAQQDE ALRLAYVGIT RAKQFCIWFA
EPKSEGVFER LPRRSNYSTQ VTVADVISLA KQVGSMEKV
//
