ID A0A0F5VRP1_9ACTN Unreviewed; 907 AA.
AC A0A0F5VRP1;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:KKD04492.1};
GN ORFNames=TN53_29565 {ECO:0000313|EMBL:KKD04492.1};
OS Streptomyces sp. WM6386.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415558 {ECO:0000313|EMBL:KKD04492.1, ECO:0000313|Proteomes:UP000033641};
RN [1] {ECO:0000313|EMBL:KKD04492.1, ECO:0000313|Proteomes:UP000033641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM6386 {ECO:0000313|EMBL:KKD04492.1,
RC ECO:0000313|Proteomes:UP000033641};
RA Ju K.-S., Doroghazi J.R., Metcalf W.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKD04492.1}.
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DR EMBL; JXTE01000058; KKD04492.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F5VRP1; -.
DR PATRIC; fig|1415558.3.peg.6703; -.
DR Proteomes; UP000033641; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.20.120.1530; -; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR013587; Nitrate/nitrite_sensing.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR Pfam; PF08376; NIT; 1.
DR Pfam; PF08447; PAS_3; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KKD04492.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000033641};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 21..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 333..385
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 436..506
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 883..907
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 907 AA; 97931 MW; 4C12699D1319998E CRC64;
MRPTRTERPA LLARLRVGRK LMLLVLLPVT GLLAFTAFSG VAQWQEASDL RAFHTTTEVS
FALTEVSDAV ARERIAAVQA RLRPSTITPA ARAAAERATD QALERAVDRT AGWTGADAAG
DLDAVGRRLH ALRVQTGTAS LTARTVAQDY AGIEDALLDS VAVFESGSPT QTSGRAADAH
IALVRAIEAA ERERVELAIL LDAPPEQGPT TAGRWPELEA AELDTFKQNT SDELRGELYS
TQFEAPGRAV RNVRETLVAP GPKTVHRPSY DSWLTDSTAR IDSLRGIQDH AARALDVTAA
RDRHSAETRV RRDLAVSLAV LGLVTLLALA LRHSITRPLS EVSQGARALS YGDLSYDIRY
AGRDELGDVA DTFRELRVTT ERLAGEIRAM NTAIDDNRLG HRADVASFDG TWAQLLGGMN
GTMASFAAAH GRREKAEQEV ESIFNLSLDL LCISGLDGYF KRVNPAFERT LGHSGEELLS
RPYIEFVHED DRDSTRVALD RLASGVDVVE FENRYLRADG TECRLQWSAR PVPEEGLIYA
TARDVTESRR AALEQAALRR VATLVARGAP PSEVFTRVAE EVGALLNTTA AVLRQEPDGS
HTVLGTAYGI PEELERASRE ERRQAGLKAM REVSGTRRAA HVGQVVGAPI VVDDRLWGFI
LAASPLDALP GGTESRLADF TELIATAIAN ADSRAQLTAS RARVVAASDA SRRRIERDLH
DGVQQRLVAL QLDLRLAESL LTDQSSELAE QLAHVSKGLD DAFQDLLQVA RGIHPAILSK
GGLGPALRSL ARRSAVPVEL DLKLPVTRLS EQLEVAAYYV TSECLTNAAK HAHARVVEVG
AEIRDDWLEM VIRDDGVGGA EPGRGSGLIG LIDRVEAIGG KLDVSSPPGE GTTMGVRLPL
SPPSTNV
//
