ID A0A0F5Y9K3_9CYAN Unreviewed; 791 AA.
AC A0A0F5Y9K3;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Alkaline phosphatase {ECO:0000313|EMBL:KKD35322.1};
GN ORFNames=WN50_25955 {ECO:0000313|EMBL:KKD35322.1};
OS Limnoraphis robusta CS-951.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Sirenicapillariaceae; Limnoraphis.
OX NCBI_TaxID=1637645 {ECO:0000313|EMBL:KKD35322.1, ECO:0000313|Proteomes:UP000033607};
RN [1] {ECO:0000313|EMBL:KKD35322.1, ECO:0000313|Proteomes:UP000033607}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CS-951 {ECO:0000313|EMBL:KKD35322.1,
RC ECO:0000313|Proteomes:UP000033607};
RA Willis A., Parks M., Burford M.A.;
RT "Draft genome assembly of filamentous brackish cyanobacterium Limnoraphis
RT robusta strain CS-951.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|PIRSR:PIRSR601952-2};
CC Note=Binds 1 Mg(2+) ion. {ECO:0000256|PIRSR:PIRSR601952-2};
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|PIRSR:PIRSR601952-2};
CC Note=Binds 2 Zn(2+) ions. {ECO:0000256|PIRSR:PIRSR601952-2};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKD35322.1}.
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DR EMBL; LATL02000043; KKD35322.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F5Y9K3; -.
DR PATRIC; fig|1637645.4.peg.735; -.
DR Proteomes; UP000033607; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016791; F:phosphatase activity; IEA:InterPro.
DR CDD; cd16012; ALP; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 2.
DR Gene3D; 2.150.10.10; Serralysin-like metalloprotease, C-terminal; 2.
DR InterPro; IPR001952; Alkaline_phosphatase.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR018511; Hemolysin-typ_Ca-bd_CS.
DR InterPro; IPR001343; Hemolysn_Ca-bd.
DR InterPro; IPR011049; Serralysin-like_metalloprot_C.
DR PANTHER; PTHR11596; ALKALINE PHOSPHATASE; 1.
DR PANTHER; PTHR11596:SF5; ALKALINE PHOSPHATASE; 1.
DR Pfam; PF00245; Alk_phosphatase; 2.
DR Pfam; PF00353; HemolysinCabind; 2.
DR PRINTS; PR00313; CABNDNGRPT.
DR SMART; SM00098; alkPPc; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR SUPFAM; SSF51120; beta-Roll; 2.
DR PROSITE; PS00330; HEMOLYSIN_CALCIUM; 1.
PE 4: Predicted;
KW Magnesium {ECO:0000256|PIRSR:PIRSR601952-2};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR601952-2};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000033607};
KW Zinc {ECO:0000256|PIRSR:PIRSR601952-2}.
FT REGION 635..659
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 173
FT /note="Phosphoserine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR601952-1"
FT BINDING 224
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000256|PIRSR:PIRSR601952-2"
FT BINDING 226
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000256|PIRSR:PIRSR601952-2"
FT BINDING 437
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000256|PIRSR:PIRSR601952-2"
FT BINDING 442
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR601952-2"
FT BINDING 446
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR601952-2"
FT BINDING 487
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR601952-2"
FT BINDING 488
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR601952-2"
SQ SEQUENCE 791 AA; 83902 MW; 010E73FE128C2B07 CRC64;
MENNKFSTKN FVVRVNREEN ISNMAKNVII MIGDGMGWEM ARAGAIAKTG ESYTSGVGEG
LSFQELDGYS FVTTYGTTIA PGSEEPNPAN RVFNTSNSAL YGSGSNLTGT NPLRPDFVFE
PDFNAGIDAS GGAANPGTTA IGNLVGYDPE RGGINPWTPG NDPEYIKYSY PDSANTATTL
YTGVKSYNSA IGVDIYEQPL ESILQIAADS DKSTGLVSSV PIDHATPGAA AANVNRRNKY
DSEFPTLDSI LQQELRIYKP TVILGGGHPL STPEDPLPGE VEPPSDNTFI LESTYQELSA
NPTDNVYGYT FLERGEDAAA VLAETAAEID PNQGERLLGL YGARGQNGNL PVSSADGDYS
TTGLDMFSLF SSAQAGSPNN ITPGVPNPDT ERPLLPGETD ESFIAREINE NPTLQDLTEA
ALDVLAKDED GFWLMIEGGD IDWSAHDNNM DNLIGTMLDF DKSVQSVMDW IEENGGWEEN
LLVVTADHDH YLTLSPDFPE LLATEGAEAL TYELHTPEES GQYWGSDPEV KYGWGSHTNR
PVPVYYQGEG SEVLDGLVGE GYNSYGFEIP GLPNHVDQTH IFQTMAAAVT GTDNYINGSQ
NAETFVGEAG NDLIIALGDN DTVAGLAGDD QIYGGDGNDV LRGDENERSP GGQPGGDDMI
YGGTGNDRIG GKGGNDKLYG DDGDDQIWGD DGDDLLHGGF GNDTLTGDDF SGGQGADTFV
LALGEGTDTI TDFELGIDKL ALTAGLTFEQ LSITASGSNA LISVGDERLA ILNGVEAVGL
IENSAATFAQ I
//
