ID A0A0F5YEV7_9CYAN Unreviewed; 884 AA.
AC A0A0F5YEV7;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 13-SEP-2023, entry version 40.
DE RecName: Full=DNA mismatch repair protein MutS {ECO:0000256|HAMAP-Rule:MF_00096};
GN Name=mutS {ECO:0000256|HAMAP-Rule:MF_00096};
GN ORFNames=WN50_15200 {ECO:0000313|EMBL:KKD37293.1};
OS Limnoraphis robusta CS-951.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Sirenicapillariaceae; Limnoraphis.
OX NCBI_TaxID=1637645 {ECO:0000313|EMBL:KKD37293.1, ECO:0000313|Proteomes:UP000033607};
RN [1] {ECO:0000313|EMBL:KKD37293.1, ECO:0000313|Proteomes:UP000033607}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CS-951 {ECO:0000313|EMBL:KKD37293.1,
RC ECO:0000313|Proteomes:UP000033607};
RA Willis A., Parks M., Burford M.A.;
RT "Draft genome assembly of filamentous brackish cyanobacterium Limnoraphis
RT robusta strain CS-951.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein is involved in the repair of mismatches in DNA.
CC It is possible that it carries out the mismatch recognition step. This
CC protein has a weak ATPase activity. {ECO:0000256|HAMAP-Rule:MF_00096}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|HAMAP-Rule:MF_00096,
CC ECO:0000256|RuleBase:RU003756}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKD37293.1}.
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DR EMBL; LATL02000340; KKD37293.1; -; Genomic_DNA.
DR RefSeq; WP_046279405.1; NZ_LATL02000340.1.
DR AlphaFoldDB; A0A0F5YEV7; -.
DR PATRIC; fig|1637645.4.peg.6685; -.
DR OrthoDB; 9802448at2; -.
DR Proteomes; UP000033607; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:UniProtKB-UniRule.
DR CDD; cd03284; ABC_MutS1; 1.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00096; MutS; 1.
DR InterPro; IPR005748; DNA_mismatch_repair_MutS.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01070; mutS1; 1.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00096}; Reference proteome {ECO:0000313|Proteomes:UP000033607}.
FT DOMAIN 742..758
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT BINDING 668..675
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00096"
SQ SEQUENCE 884 AA; 99448 MW; D3A97A53CAC9C657 CRC64;
MTDPTPASTP PEEYPNADYR QLDRSKLSEM MQRYLEVKEQ YPHALLFFRV GDFFECFFQD
AVTIAHELEL MQTTKAAGKE VGRVPMTGVP HEHVYRYSST LLEKGYAVVI CDQVEDAAIA
AKEKRQVKRE VTRVLTPGTL TDDNMLKGRQ NNYLAALVIA GEHWGLAYAD ISTGEFLITQ
SVNLEQLTQE LMRLQPSEVL VPVNAPDISK MLKPGESDHE LPDCLPRCFC YSLRSQKPFS
LGEARPRVLQ QFQLKSLEGI GCEHLPLSVR AAGGLLEYLE DTQKHNTTSL QRPRTYTLSD
YLILDHQSRR NLEITTTVRD NTLYGSLLWA LDKTNTPMGS RALRRWLLQP LLDLKGIRAR
HDTIQEFVNN HQLRQDFQQL LRQIYDLERL TGRVGNNTAN AKDLVSLADS LAKLPQLAAL
AEQAKSPYLK ALQNLPQSLE KIAEKIHNYL VESPPIHLKE GGLIRSGVDA NLDEMRSLAT
DDQQWIANLE VQERERTGIA TLKVGYNKAF GYYISISRGK AELAPDDYLR KQTLTNEERY
ITPELKEREV RILTAKEDLN QAEYDIFVRL RSEVAEYTDI IRNVSRAIAA IDVLCGLAEV
ADRQGYCRPE MVKGRELKII DGRHPVVEKL LPPGFFVPNT AQLGSIENHT ENTEIPPYSY
PDLIILTGPN ASGKSCYLRQ IGLIQLMAQM GSFIPASSAK LSLCDRIFTR VGAVDDLATG
QSTFMVEMNE TANILNHATN KSLVLLDEIG RGTATFDGLS IAWSVAEYLA TEIQAKTIFA
THYHELNELA SILDNVANYQ VTVKELPDKI VFLHQVQPGG ADKSYGIEAG RLAGLPDVVI
QRARQVMRQI EQHSKIAIGL RKGIKKQTNK STSMEQLDIF ETED
//
