ID A0A0F5ZSH1_9GAMM Unreviewed; 494 AA.
AC A0A0F5ZSH1;
DT 24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT 24-JUN-2015, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=methylmalonate-semialdehyde dehydrogenase (CoA acylating) {ECO:0000256|ARBA:ARBA00013048};
DE EC=1.2.1.27 {ECO:0000256|ARBA:ARBA00013048};
GN ORFNames=RN22_23710 {ECO:0000313|EMBL:KKD57945.1};
OS Grimontia sp. AD028.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Grimontia.
OX NCBI_TaxID=1581149 {ECO:0000313|EMBL:KKD57945.1, ECO:0000313|Proteomes:UP000033732};
RN [1] {ECO:0000313|EMBL:KKD57945.1, ECO:0000313|Proteomes:UP000033732}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AD028 {ECO:0000313|EMBL:KKD57945.1,
RC ECO:0000313|Proteomes:UP000033732};
RA Adrian T.-G.-S., Chan K.-G.;
RT "Genome sequencing of Grimontia sp. AD028.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKD57945.1}.
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DR EMBL; LASY01000166; KKD57945.1; -; Genomic_DNA.
DR RefSeq; WP_046308373.1; NZ_LASY01000166.1.
DR AlphaFoldDB; A0A0F5ZSH1; -.
DR PATRIC; fig|1581149.3.peg.1249; -.
DR OrthoDB; 9812625at2; -.
DR Proteomes; UP000033732; Unassembled WGS sequence.
DR GO; GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity; IEA:InterPro.
DR CDD; cd07085; ALDH_F6_MMSDH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR010061; MeMal-semiAld_DH.
DR NCBIfam; TIGR01722; MMSDH; 1.
DR PANTHER; PTHR43866; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43866:SF4; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 14..474
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
SQ SEQUENCE 494 AA; 52840 MW; 98213E9E3E957836 CRC64;
MSVTHYIDGK YTAESERKQA LFNPATGEQS GEVSLASVAE TEAAIASAKA AFPAWSEMSP
LRRARVMFKF KALVEENIDE LAALITKEHG KVLDDAKGEL TRGLEVVEFA CGIPHLLKGE
MTEQIGSGID AWSLNQPLGV VAGISPFNFP VMVPMWMFPI AIACGNTFVM KPSEKDPSST
LRIAELLTEA GLPDGVFNVV NGDKEAVDVL LTHPDVQAVS FVGSTPIAEY IYSTASAHGK
RVQALGGAKN HMVVMPDADL DQAVAALMGA AYGSAGERCM AISVAVAVGN VADALIEKLT
PKVKELRVGN GVIEGMEMGP LVTKEHLSKV EGYVAKGVEE GADLLVDGRG VQAEGGDGYF
LGGCLFDNVT PEMTIYRDEI FGPVLSVVRV PDYATAVKLI NDHEFGNGTA IFTQNGDAAR
QFCHEIQVGM VGVNVPIPVP MAFHSFGGWK RSLFGSLHVH GPDGVRFYTR RKAITARWPT
GLRANADFIM PTMK
//
