ID A0A0F7FS82_9ACTN Unreviewed; 508 AA.
AC A0A0F7FS82;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Xylosidase/arabinosidase {ECO:0000313|EMBL:AKG42873.1};
GN ORFNames=SXIM_14890 {ECO:0000313|EMBL:AKG42873.1};
OS Streptomyces xiamenensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=408015 {ECO:0000313|EMBL:AKG42873.1, ECO:0000313|Proteomes:UP000034034};
RN [1] {ECO:0000313|Proteomes:UP000034034}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCCC 1A01550 {ECO:0000313|Proteomes:UP000034034};
RA Xu J.;
RT "Complete genome sequence of a mangrove-derived Streptomyces xiamenensis.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}.
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DR EMBL; CP009922; AKG42873.1; -; Genomic_DNA.
DR RefSeq; WP_030725809.1; NZ_CP009922.3.
DR AlphaFoldDB; A0A0F7FS82; -.
DR STRING; 408015.SXIM_14890; -.
DR KEGG; sxi:SXIM_14890; -.
DR PATRIC; fig|408015.6.peg.1525; -.
DR HOGENOM; CLU_016508_2_0_11; -.
DR Proteomes; UP000034034; Chromosome.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd18617; GH43_XynB-like; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR041542; GH43_C2.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR42812; BETA-XYLOSIDASE; 1.
DR PANTHER; PTHR42812:SF12; BETA-XYLOSIDASE-RELATED; 1.
DR Pfam; PF17851; GH43_C2; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361187};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361187}.
FT DOMAIN 313..501
FT /note="Beta-xylosidase C-terminal Concanavalin A-like"
FT /evidence="ECO:0000259|Pfam:PF17851"
FT ACT_SITE 24
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 180
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 132
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 508 AA; 54898 MW; CD140E67960A9F1F CRC64;
MKATADGWAG GTFSNPVIPG FHPDPSICRV GEDYYLVCSS FEYFPGVPVF HSKDLVHWEQ
IGNVMERPAQ LRLPDTAPSS GGVYAPTLRH HDGRFWLITT DVSHDGNVLF SATDPAGPWS
DPVRLPGVKG IDPDLAWDED GRCWVTTAGI SQICIDPGTG QTIGAPRRLW SGTPGAKAPE
APHLYRIGDH WYLLIAEGGT ERGHGISIAR GPAPYGPFEP CPDNPVLSHR STDLEIQNTG
HGDLVQAPDG SWWLVFLGVR PGGGSPGWHV LGRETFLAPV TWTDGGWPVI GAATPAMAAP
PWPPRPVPAP PARDDFDAAR LHPHWLSVRS RPEGYFSTTE RPGWLTLRAR GASLDDQAVT
FAGRRQQDRS CRARTLIDPG VGLGGLAVRL DERHHYAVEA AGTGTVRVVA RIGPLRQTLG
ERRVPAGPVT LRIDISAPTE TWDPRQGPDV LRLGVEGPDG ELEVLAELDG RYLSTEVAGG
FTGRVIGMYA AEGTVRFDWF ALEAGDKE
//
