ID A0A0F7JUB7_9GAMM Unreviewed; 326 AA.
AC A0A0F7JUB7;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=2-oxoisovalerate dehydrogenase {ECO:0000313|EMBL:AKH19227.1};
GN ORFNames=AAY24_01455 {ECO:0000313|EMBL:AKH19227.1};
OS Sedimenticola thiotaurini.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Sedimenticola.
OX NCBI_TaxID=1543721 {ECO:0000313|EMBL:AKH19227.1, ECO:0000313|Proteomes:UP000034410};
RN [1] {ECO:0000313|EMBL:AKH19227.1, ECO:0000313|Proteomes:UP000034410}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SIP-G1 {ECO:0000313|EMBL:AKH19227.1,
RC ECO:0000313|Proteomes:UP000034410};
RX PubMed=26089430;
RA Flood B.E., Jones D.S., Bailey J.V.;
RT "Complete Genome Sequence of Sedimenticola thiotaurini Strain SIP-G1, a
RT Polyphosphate- and Polyhydroxyalkanoate-Accumulating Sulfur-Oxidizing
RT Gammaproteobacterium Isolated from Salt Marsh Sediments.";
RL Genome Announc. 3:e00671-15(2015).
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR EMBL; CP011412; AKH19227.1; -; Genomic_DNA.
DR RefSeq; WP_046858166.1; NZ_CP011412.1.
DR AlphaFoldDB; A0A0F7JUB7; -.
DR KEGG; seds:AAY24_01455; -.
DR PATRIC; fig|1543721.4.peg.308; -.
DR OrthoDB; 9780894at2; -.
DR Proteomes; UP000034410; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000034410};
KW Thiamine pyrophosphate {ECO:0000256|ARBA:ARBA00023052}.
FT DOMAIN 4..179
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 326 AA; 35541 MW; 28CAFEE5E0D8F0F7 CRC64;
MTEITLVEAV NLALMHEMER DPAMVILGQD IGVNGGVFRA TVGLLEKFGS ERVLDTPLAE
NMIAGTAVGM ATQGLHPVAE IQFMGFIPPT IDQLISHASR MRNRTRGRLS CPMVLRAPYG
GGIHAPEHHS ESTEAMFAHI PGIRVVIPSS PTRAYGLLLA AIRDPDPVVF LEPKRVYRLM
KQAVEDNGEA LPLDTCFVLR PGSDITLVSW GAMLHETQQA AEQLAGEGIE AEVIDLATIK
PIDMETILES VGRTGRCVIV QEAARTCSVS AEIAARLAEE GLMSLFAPIR RVTGFDTVMP
MFRLEGHYMP GTERIIDAVR QTMEYA
//
