ID A0A0F7MZU9_9ACTN Unreviewed; 1080 AA.
AC A0A0F7MZU9;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Alpha-mannosidase {ECO:0000313|EMBL:AKH81231.1};
GN ORFNames=AA958_02510 {ECO:0000313|EMBL:AKH81231.1};
OS Streptomyces sp. CNQ-509.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=444103 {ECO:0000313|EMBL:AKH81231.1, ECO:0000313|Proteomes:UP000034283};
RN [1] {ECO:0000313|EMBL:AKH81231.1, ECO:0000313|Proteomes:UP000034283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CNQ-509 {ECO:0000313|EMBL:AKH81231.1,
RC ECO:0000313|Proteomes:UP000034283};
RA Ruckert C., Albersmeier A., Leipoldt F., Winkler A., Zeyhle P.,
RA Kalinowski J., Heide L., Kaysser L.;
RT "Complete Genome Sequence of Streptomyces sp. CNQ-509, a Prolific Producer
RT of Meroterpenoid Chemistry.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR EMBL; CP011492; AKH81231.1; -; Genomic_DNA.
DR RefSeq; WP_047014594.1; NZ_CP011492.1.
DR AlphaFoldDB; A0A0F7MZU9; -.
DR STRING; 444103.AA958_02510; -.
DR KEGG; strc:AA958_02510; -.
DR PATRIC; fig|444103.5.peg.537; -.
DR OrthoDB; 237949at2; -.
DR Proteomes; UP000034283; Chromosome.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR CDD; cd10791; GH38N_AMII_like_1; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR PANTHER; PTHR11607; ALPHA-MANNOSIDASE; 1.
DR PANTHER; PTHR11607:SF3; LYSOSOMAL ALPHA-MANNOSIDASE; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000034283};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 140..437
FT /note="Glycoside hydrolase family 38 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01074"
SQ SEQUENCE 1080 AA; 116045 MW; D10A587ADA4E3E58 CRC64;
MTTRALVKTT DWDNDRIRDS LRGSVVSAEG SLAGTALRLT QEPLLKHAEG GGLLQSLRVE
ATGGPLPAEL AAGSSTAFVV RTESGTALPA VPEAGPGGSV RLLLPAVDTA TRVTVGLAAD
PDAGADAGIV LTLTPQRQWT LHLVHHSHLD IGYTDPQGRV LAEHLSFLDS CLELTRATDD
WPAESRFRWC VESLWSFRQW ADARPAEQVE EFVRRVREGR IELTAMPFNL HTETCSTDEL
HELLRLADEV RDEHGVEFTS AMQTDVPGAV VGLVDALAAA GVRYLSVAHN WAGRSVPHLV
GGEKLPRLFR WRAPSGNSIL VWVTDTPHGL AYMEGPLLGF DTDYDSVDDL LPAYLTSLAS
NPYPYRGGIF GWAMDQADVK REPYPWDILH LRVQGKFGDN APPRRIIADT VRRWNETWAY
PQLRLSRNED FFTDAEARLG DEIRTFEGDW TDWWVDGVGS GARPLSLART AQATVADAQT
LGTFAGILGA TGAADDSRDA APVYEAVSLF DEHTWGAGDP WTHGDHGGHS GEEQWHWKYG
QALRAYDDGN SLLDRARARL GQRLAGAPDA VSYHVVNTCS WARTDVVRIF LPESSVPLEQ
RVAVRDARTG EKLRHEEQAQ VNDDHRDAGR FLLVCVADVP PAGSVRLDVV AEGAGDGAAD
GEGTVLKAAT GWNPTGGTEK EDPAETAAAA HAQADPTLLE NEHLAVRVDL ARACIASVVD
KTTGRELVRG ADAGAAAGFN AYIHDSYTTA GGFNHNSSRT TASERLEHLG NRSVAPPAAL
IARTSTATGE TLTYETRPAG ANRVRTTLTL PHGAARLDIE NRVDKDATPG KESAYFAFPF
AFEAPTVRME ATGGATGTGL SVIPGSARHM RAVRRWVTLA DDGLAVAWAT QDAPLVQFGN
IALPYAPFPK TMGEDEPATV FSWIHNNLWD TNFPSEQGFE FTFRYSLACG TDAAAPHGSL
GARTAAGLSR PLHAVRARAP HAEGPEVTDG LAFAEVGDPR VRLVGATTPG GEAGEGAVLL
RLQSFAEEPV ACPVRALFPV TGAGLADYLG RPGDDLPVTD GEVTVDLPTL GTTAVLFRRR
//
