ID A0A0F7ZL31_9HYPO Unreviewed; 1071 AA.
AC A0A0F7ZL31;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=NFACT RNA-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=HIM_04755 {ECO:0000313|EMBL:KJZ75931.1};
OS Hirsutella minnesotensis 3608.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Hirsutella.
OX NCBI_TaxID=1043627 {ECO:0000313|EMBL:KJZ75931.1, ECO:0000313|Proteomes:UP000054481};
RN [1] {ECO:0000313|EMBL:KJZ75931.1, ECO:0000313|Proteomes:UP000054481}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3608 {ECO:0000313|EMBL:KJZ75931.1,
RC ECO:0000313|Proteomes:UP000054481};
RX PubMed=25359922; DOI=10.1093/gbe/evu241;
RA Lai Y., Liu K., Zhang X., Zhang X., Li K., Wang N., Shu C., Wu Y., Wang C.,
RA Bushley K.E., Xiang M., Liu X.;
RT "Comparative genomics and transcriptomics analyses reveal divergent
RT lifestyle features of nematode endoparasitic fungus Hirsutella
RT minnesotensis.";
RL Genome Biol. Evol. 6:3077-3093(2014).
CC -!- SIMILARITY: Belongs to the NEMF family.
CC {ECO:0000256|ARBA:ARBA00008318}.
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DR EMBL; KQ030514; KJZ75931.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F7ZL31; -.
DR OrthoDB; 129892at2759; -.
DR Proteomes; UP000054481; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0072344; P:rescue of stalled ribosome; IEA:UniProt.
DR Gene3D; 2.30.310.10; ibrinogen binding protein from staphylococcus aureus domain; 1.
DR InterPro; IPR021846; NFACT-C.
DR InterPro; IPR008532; NFACT_RNA-bd.
DR PANTHER; PTHR15239; NUCLEAR EXPORT MEDIATOR FACTOR NEMF; 1.
DR PANTHER; PTHR15239:SF6; RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF; 1.
DR Pfam; PF11923; NFACT-C; 1.
DR Pfam; PF05670; NFACT-R_1; 1.
DR Pfam; PF05833; NFACT_N; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000054481}.
FT DOMAIN 550..663
FT /note="NFACT RNA-binding"
FT /evidence="ECO:0000259|Pfam:PF05670"
FT DOMAIN 936..1040
FT /note="NFACT protein C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11923"
FT REGION 439..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 690..858
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 870..914
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1042..1071
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 440..460
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 690..728
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 765..799
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 812..826
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 874..914
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1071 AA; 117819 MW; CBB66CFF98C0A1C5 CRC64;
MKQRFSSLDV KVIAHELNQS LVSLRVANIY DLSSKILLFK FAKPNDKKQL VVDSGFRCHL
TEFARTTAAA PSAFVARLRK FLRTRRLTSV AQIGTDRVLE LQFSDGQYRL YLEFFASGNI
ILTDAERTIL TIARNVPEGE NQEPQRVGLQ YSLENRQNYA GIPPLSKERV RHALQAAVEK
AAADGAPQKK LKGKPGGTLR KSLAISITEI PPVVVDHVLI CNSFDTSMKL EDILGDEARL
EELVRLLLEA RKMVEQITTS SVCTGYIFAR QKDGVEIPAD AAADTLPKKE DLLYDDFHPF
VPAMIRNNPL MKILEFQGYN QTVDEFFSSL EGQKLETRLT QKEATAKRKL EAARLDQAKR
LEGLQEAQSM NLRKAAAIEA NLERVQEAMN AVNGLLVQGM DWVDIGKLIE REKKRHNPVA
EVIELPLKLA ENIVTLKLSE EDFDDEEEED PFETDESESE EDQSAAKARS ARQFDKALTV
EINLGLSPWS NAREYYDQKR TAAAKEEKTQ LQATKALKSA EQKITEDLKK GLKQEKALLQ
PIRKQSWFEK FLWFVSSDGY LVIGGKDATQ NELLYRKHLR KGDVYCHADL NGAPSVIIKN
NPKTPDAPIP PATLSQAGSL SVCASDAWDS KAGMGAWWVN ADQVSKSAST GEFLATGSFT
VRGNKNHLPP AQLLLGLGVM FRISEESKAR HVKHRLQEGD SMDKPPPTED HANHPRKPAI
AKEIDAGDVD ENNDSDGLSE PESEMEQGTP DRENPLQAFG GRTEDNDIAE MEAEVSKLDV
RDQTAVEEAS QRDASEDGPE GQEPPETVAD SAEGSNKASE TSKPQPPGPK TDKKAPVKRG
QKGKAKKMAS KYKDQDEEDR LAAEALIGAA AGKRRAEAEA KAKEDARAEL EAAKERRRAQ
HQRQQRETAE HEEIRRAMME QGAVDTLDGD EAEAATAGLD DLVGTPLPGD EILEAIPVCA
PWAALGRFKF KAKMQPGATK KGKAIKEVLE RWRADSAKKG AVDDSARDME KMWPREVALL
KALKPEEVIN SVPASKVRVM MAGGGGGGGG GGKGGGKGQA KGGRGGRGSK R
//
