ID A0A0F8AN84_LARCR Unreviewed; 538 AA.
AC A0A0F8AN84;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=ribonuclease H {ECO:0000256|ARBA:ARBA00012180};
DE EC=3.1.26.4 {ECO:0000256|ARBA:ARBA00012180};
GN ORFNames=EH28_00455 {ECO:0000313|EMBL:KKF24066.1};
OS Larimichthys crocea (Large yellow croaker) (Pseudosciaena crocea).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Sciaenidae; Larimichthys.
OX NCBI_TaxID=215358 {ECO:0000313|EMBL:KKF24066.1};
RN [1] {ECO:0000313|EMBL:KKF24066.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SSNF {ECO:0000313|EMBL:KKF24066.1};
RC TISSUE=Blood {ECO:0000313|EMBL:KKF24066.1};
RX PubMed=25835551;
RA Ao J., Mu Y., Xiang L.X., Fan D., Feng M., Zhang S., Shi Q., Zhu L.Y.,
RA Li T., Ding Y., Nie L., Li Q., Dong W.R., Jiang L., Sun B., Zhang X.,
RA Li M., Zhang H.Q., Xie S., Zhu Y., Jiang X., Wang X., Mu P., Chen W.,
RA Yue Z., Wang Z., Wang J., Shao J.Z., Chen X.;
RT "Genome Sequencing of the Perciform Fish Larimichthys crocea Provides
RT Insights into Molecular and Genetic Mechanisms of Stress Adaptation.";
RL PLoS Genet. 11:E1005118-E1005118(2015).
CC -!- SIMILARITY: Belongs to the beta type-B retroviral polymerase family.
CC HERV class-II K(HML-2) pol subfamily. {ECO:0000256|ARBA:ARBA00010879}.
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DR EMBL; KQ041655; KKF24066.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0F8AN84; -.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF00665; rve; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 3: Inferred from homology;
FT DOMAIN 1..82
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT DOMAIN 178..337
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 445..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 479..501
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 538 AA; 60135 MW; FE4A92D9606C445F CRC64;
MPFGLTNAPA VFQALVNDIL RDMLNKFVFV YLDDILIFSK TQSEHVHHVQ SVLRRLLENS
LYVKAEKCEF HVRTTSFLGF IVAEGHIQMD PAEVSAVSSW PIPESRKKLQ QFLGFANFYR
RFIRGYSAVA APLTSLTSTK RPFEWTPAAD RAFQSLKARF TSAPILRMPD EECPPLPIPM
RPWSHVALDF VSGLPPSDGN TVILTIVDRF SKMAHFIPLP KLPSAKETAQ IVLEQVFRIH
GLPKDIVSDR GPQFASSFWK EFCHLLGATA SLTSGFHPQS NGQAERINQE LEKALRCMAS
RNPRAWAQHL LWIEYAHNSL TSTATGLSPF QCVYGYQPPL FASQEGNITC PSALAYARRC
RRTWYELTIM DPAGEHSNME TSPEPSALEH LGRAESDMRR MTSDIASLVR LGHQHQQQVQ
QQQQRILGQE QQLAQVIQLL TQLTTPSAPV SPDPSIPDPG SQGSNIQVPL QPVSVLRWRR
SSRHHVSSKS RSSPGVGEIR VSSTILQSPP IRKTLLQVHL RLPNTSHTLA ALVDSGAT
//
