ID A0A0F8B1E8_CERFI Unreviewed; 1999 AA.
AC A0A0F8B1E8;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=1-phosphatidylinositol 4-kinase {ECO:0000256|ARBA:ARBA00012169};
DE EC=2.7.1.67 {ECO:0000256|ARBA:ARBA00012169};
GN Name=STT4 {ECO:0000313|EMBL:KKF95011.1};
GN ORFNames=CFO_g2652 {ECO:0000313|EMBL:KKF95011.1};
OS Ceratocystis fimbriata f. sp. platani.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Microascales; Ceratocystidaceae; Ceratocystis.
OX NCBI_TaxID=88771 {ECO:0000313|EMBL:KKF95011.1, ECO:0000313|Proteomes:UP000034841};
RN [1] {ECO:0000313|EMBL:KKF95011.1, ECO:0000313|Proteomes:UP000034841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFO {ECO:0000313|EMBL:KKF95011.1,
RC ECO:0000313|Proteomes:UP000034841};
RA Belbahri L.;
RT "Genome sequence of Ceratocystis platani, a major pathogen of plane
RT trees.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the PI3/PI4-kinase family. Type III PI4K
CC subfamily. {ECO:0000256|ARBA:ARBA00006209}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKF95011.1}.
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DR EMBL; LBBL01000125; KKF95011.1; -; Genomic_DNA.
DR Proteomes; UP000034841; Unassembled WGS sequence.
DR GO; GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05167; PI4Kc_III_alpha; 1.
DR Gene3D; 1.10.1070.11; Phosphatidylinositol 3-/4-kinase, catalytic domain; 1.
DR Gene3D; 1.25.40.70; Phosphatidylinositol 3-kinase, accessory domain (PIK); 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR036940; PI3/4_kinase_cat_sf.
DR InterPro; IPR018936; PI3/4_kinase_CS.
DR InterPro; IPR001263; PI3K_accessory_dom.
DR InterPro; IPR042236; PI3K_accessory_sf.
DR InterPro; IPR045495; PI4K_N.
DR InterPro; IPR015433; PI_Kinase.
DR PANTHER; PTHR10048:SF15; PHOSPHATIDYLINOSITOL 4-KINASE ALPHA; 1.
DR PANTHER; PTHR10048; PHOSPHATIDYLINOSITOL KINASE; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR Pfam; PF00613; PI3Ka; 1.
DR Pfam; PF19274; PI4K_N; 1.
DR SMART; SM00145; PI3Ka; 1.
DR SMART; SM00146; PI3Kc; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00915; PI3_4_KINASE_1; 1.
DR PROSITE; PS00916; PI3_4_KINASE_2; 1.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
DR PROSITE; PS51545; PIK_HELICAL; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KKF95011.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000034841};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KKF95011.1}.
FT DOMAIN 1393..1580
FT /note="PIK helical"
FT /evidence="ECO:0000259|PROSITE:PS51545"
FT DOMAIN 1714..1983
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
SQ SEQUENCE 1999 AA; 221348 MW; 4486702A98284AED CRC64;
MARDFRQRAL DKIASLAATS SYSSFDRSDF DRLCSACSTA TRAKDAANGF VPNTRSVAGA
PAPMARVPMT IREFQVLVSL CKAAPNIHSV QNAQRLAYQL APYIQEAHMQ LFAPSPYFRK
VEPSPSESLT FHVSAALLHL GKAFPELQDR ISDNLWAYLA SCAAVAEKIE PPQDDDEPNL
DDAMHTATIA VSLLGFLDAV ASQPDFWTPA SRLSLVQNVR RLLSDRFLVA METAFSTLRV
APTGHRTVKE WKRYLKHYTL SGRPLSSMLV QRSFTWLLIS VTSLLIVPAN ELRGSHILDV
LMSGKELPEP VAVRTGDANT DTISVYTKMA TASMLYFEAG ADFVVQLGSS LQQRLAFSVK
SAALIAYVNC AVLNDDAADP DTIMAWLEEI LADPVQMADE LLASTVLRGL AVLCRLSPDY
ALGVSRLLPR FIIQSSPNQN IIALASHSLA YVLQILSKDA VITTLYSLGN FLSPASERPR
AKELANGTGP AAVSGPETAP EPANGYGALY SEGVTTGSFM SLSGDAAEEA GVVHANVVQA
ICGIAQDCND EKITALAQSM LLQKFGKVNS QVDAQLIAAA GALALKSGVL EFRSLLKMYA
RISHQGVSEN SENLLDAVMK ARTYLSTHLN RDSPLYSIYW EYLLDSVIAL GDVSRQDHTK
EADVQLAARE IAQLLKPLAV FMSTSNPALA TAEGDKSFGL LRDAWFNITV YGFLPSTDRG
KAHLADLRTI ALHSPPLVAE QPGEKIESDI ELNTVLRRAM SSEREAIQKK SLSELLPSRA
SEIRGLSYRK VIFLQAVYLV ESLRADAGDC TKALSYFVEP SMRKGDLSGP MDVIAATVVD
KYLHKTLQAA DPAFSAQYVA YQLASIFSSC CHRVERVQQA AFACADRILN DVPSALCYRS
SLFALLELLS LMWTGCLEAE TDVYDPRSVF TSSLGKVTIE LSQNYTHRRS TMDLLYRKAK
SWVTAALALA PADVKGLLQT YLSEYDDAGA YGHISLGRSF ALEMGSLLPS TDQRLQAMDR
IGDISVNTAS DFIAQYTTRQ EYRFGETLPT RGTELLSYMR ANNRHESFML GKGPEAATSL
NESASAATAL QHIEARILSR KPTPLSEVRE ILRRAAALLC RSPHDETAAA HHLVSIPFAM
FTRRSLKLGV SLWLGVVNEN PRLEPRLLNE IAHHWEATVH KKQGMFNPAL AHPDPFFLRC
DFSPTDLKAL AKRKQLVHNL LSPHTSLLQF FTSHFNATRL GSPDTQRIFL RLLDTTLDAL
RHTSAHPLAR DLRFQIVLFG LRVLRLSSTI GAVAQWRLKD KILSAALGWF RFAPRWSFGS
NLLQMKTELR LLSDVMTALK AVNSIGAQGT NNIRSLQAKE QLLNLLLESE LQRLAVWVYP
LPDSAKHAGI ASARARNTIE AELIPLVRTA WSQDPSIAIE LVSRFNWPRI HKEVRWLLLN
VPSNAINEPE ALPVLFGGKL PEDVTFLQLK HLLFWAPVNP LTAVTLFLPE YKNNPFVMQY
AMRALESHPI NVTFFYVPQI VQTLRYDALG YVERYILETA QFSQLFAHQI IWNMKANAYK
DDDGQIPDEL KPTLDNIMNK MVASFSVEDR VFYEREFAFF DEVTGVSGKL KPFIKSSREI
KKQKIEEELR KIKVEVGVYL PSNPDGVVIG IDRKSGKPLQ SHAKAPYLAT FRVQKRDVDD
GGDDLMQLPL DDSDPAPEGG ADVTIALNNN TAPKANGVSE ANSTVPPNAV VASVPAPMEV
WQSCIFKVGD DCRQDVLALQ MIAAFRGIFN SVGLDVFVYP YRVIATAPGC GVIEVLPNSI
SRDMLGREAV NKLYDYFVSK YGNEDSLRFQ AARANFVKSM AAYSVISFLL QFKDRHNGNI
MIDDQGHILH IDFGFCFDIA PGGIKFERAP FKLTTEMMAV MGGSPDHQAF RWFEELCVKA
FLAARPYAHK LAEIVHLMMD SGLPCFKPES VKHFVDRFVL DKSEKEAADF MRDLIHKSYA
SYSTGIYDHF QLLTNGIPY
//
