ID A0A0G0A6M6_TRIHA Unreviewed; 1124 AA.
AC A0A0G0A6M6;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Homeobox and C2H2 transcription factor {ECO:0008006|Google:ProtNLM};
GN ORFNames=THAR02_00040 {ECO:0000313|EMBL:KKP07832.1};
OS Trichoderma harzianum (Hypocrea lixii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=5544 {ECO:0000313|EMBL:KKP07832.1, ECO:0000313|Proteomes:UP000034112};
RN [1] {ECO:0000313|Proteomes:UP000034112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T6776 {ECO:0000313|Proteomes:UP000034112};
RX PubMed=26067977; DOI=10.1128/genomeA.00647-15;
RA Baroncelli R., Piaggeschi G., Fiorini L., Bertolini E., Zapparata A.,
RA Pe M.E., Sarrocco S., Vannacci G.;
RT "Draft whole-genome sequence of the biocontrol agent Trichoderma harzianum
RT T6776.";
RL Genome Announc. 3:E0064715-E0064715(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKP07832.1}.
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DR EMBL; JOKZ01000001; KKP07832.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0A6M6; -.
DR OMA; NCYGRLE; -.
DR OrthoDB; 450547at2759; -.
DR Proteomes; UP000034112; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR11850:SF102; HOMEOBOX PROTEIN HOMOTHORAX; 1.
DR PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM00355; ZnF_C2H2; 3.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000034112};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 123..186
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 334..362
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DNA_BIND 125..187
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 99..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 180..231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 267..294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 798..821
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..118
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 188..206
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..294
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 798..812
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1124 AA; 124980 MW; DCA4B078DFE014C4 CRC64;
MAMMNPDDFI DFSGGMEDTD AAVPNESCEY CVKEHIHCQV TPETINLGGC KPCIEAKRNC
TFPSNMGAPM NVLEPLESFA GFGAAGNEHQ DQLQQLLESS YSRSESSFTG NDSLGEDSTR
GLDATPKIGA RFSREALRIL RNWLLSNHLH PYPNNEEKEN LARQTGLNKT QISTWVANAR
RRGKVRAPRS TSSSPGQLNN AIDIPQKKTP VTRGMSPMER WRHSPPDQEP ASITAIASAV
SSAGFSAAAG SGAASANYKD MDDTLPGSID RLSSAGSSKT SHSSNGSLSS AVSHKSRESL
ESLYSLKSRG RRRRRRQIPK AVDISAMLPS VHKYQCTFCT ETFKTKHDWQ RHEKSLHLSL
EQWVCSPNGP VQFCAEWDCL ACVYCGLKNP SPEHAEQHND FVCHGRPDAE KTFFRKDHLR
QHLSIVHDAK FQKWPMSDWK VDTPAVRSRC GFCGIILYSW DSRVGHLAQH FKMGKSMADW
KGDWGFQGDI LKIVENGMPP YLIHHERNTL DPFEASKDEV RHGKTLEDHV KLWLIDYINK
RTVAGMAATD DQLLIEAQRV VQKVDTEDIS LTGPDISWFR DLIMLHKPSN HMAQEELYRA
SGITSWTSQI EKMKTSKSTH ADMSAVGDEK EKLLLRYVKS RQAAGQTPTD AELQFQACKI
LDDVEPKSNF KCKEAVQWFK FLINSSSDWL SAFKRRADVL SNAETLYGQM QPVAHDIINN
GEHHLSVLQQ DSLGGISASQ VPGTATLGGE MQLESNLIIP GDGNQTILGE LSDFGVSAER
NDLLASLDDT LIAAHESGDL TSTHQAKDTK TGATPSPKAL HWGVPDEAIG CTSPMDTNDY
LPGLTETPHS ANSHPSHHQP LRYFLSDANC YGRLEKELTR FLNAKTSSDT FQIPTDEEIQ
YQARWIIYDD DDPWNQTAAD NVEWLARFKR DVGITAADSA SGLPLNGPPR PWRVTDGGTG
LTPPYLKPKP GKVIEVADEA ASVLIDHRFY NVNKDTAERY VRALCEGEYQ FPPSVFCSRE
LEDGLNAYVE DCMKALYVPS DDDLRAKARD ILGVERTAAD DPKLLETFKA MHVLWHTTNN
DFILDGHLNS NTLDFMEGVD VLASDPEHMN AFDLNTELST SLGV
//
