ID   A0A0G0J6M7_9BACT        Unreviewed;       547 AA.
AC   A0A0G0J6M7;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Type I phosphodiesterase/nucleotide pyrophosphatase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=US49_C0012G0001 {ECO:0000313|EMBL:KKQ32219.1};
OS   candidate division TM6 bacterium GW2011_GWF2_37_49.
OC   Bacteria; Candidatus Dependentiae.
OX   NCBI_TaxID=1619083 {ECO:0000313|EMBL:KKQ32219.1, ECO:0000313|Proteomes:UP000033926};
RN   [1] {ECO:0000313|EMBL:KKQ32219.1, ECO:0000313|Proteomes:UP000033926}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT   radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKQ32219.1}.
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DR   EMBL; LBTE01000012; KKQ32219.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0G0J6M7; -.
DR   Proteomes; UP000033926; Unassembled WGS sequence.
DR   GO; GO:0004035; F:alkaline phosphatase activity; IEA:InterPro.
DR   Gene3D; 3.30.1360.150; -; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR026263; Alkaline_phosphatase_prok.
DR   InterPro; IPR002591; Phosphodiest/P_Trfase.
DR   PANTHER; PTHR10151:SF120; BIS(5'-ADENOSYL)-TRIPHOSPHATASE; 1.
DR   PANTHER; PTHR10151; ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE; 1.
DR   Pfam; PF01663; Phosphodiest; 1.
DR   PIRSF; PIRSF031924; Pi-irrepressible_AP; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|PIRSR:PIRSR031924-50}.
FT   ACT_SITE        74
FT                   /note="Phosphothreonine intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR031924-50"
FT   BINDING         95
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR031924-51"
FT   BINDING         159..161
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR031924-51"
SQ   SEQUENCE   547 AA;  62054 MW;  EBEE6F304D9C7E4B CRC64;
     MKLKHIFKIL LFFWVAVPNS FGQTPKLTIV LVVDQFAYHY FQRLSPYFTH GLKLLQENGV
     NFQNAHHPHA APTTATGHVT LSTGALAKDH GVILNSWSES GIHRKFSSDD SPQAAELTKN
     GTADYGHSAH QIMTDTISDQ FIINSRPDDA NYVYSLSLKS RAAIGMAGKM GKAVWFDNDQ
     GKFTSSKAYF EKWPSWLTKF NKENNLKKLT EIDWTLSYPP NSEPYKFFNI QNYKHSKSQN
     RLAGQLIKIN GDKDFSIFQK TPYGNELLLS MGRQLIDTNI EKINTGKMLL WISLSSLDKI
     GHDFGPYSME VIDMVYNLDM QLEPFIHHAQ DQFGAENVLF VLTADHGVAP IQEILEDEGF
     AIPSRVDSKK LTADMNAHVK EKFEIDNIIQ EFRTNQFYFN KEALTGVDKK QRKEICSSLQ
     EFLSTYPAIK CSWTHDELVK TKFSKNHYEQ LFKNQLYPGR SGDLVVMSQP YCTIIKHSKG
     ATHRSPYEYD THVPLIFYQE GVLSNKAVLR KVLATQIAPS LAKILHVPAP ATASNKVLPE
     LFEVAAN
//