ID   A0A0G0K1L5_9BACT        Unreviewed;       450 AA.
AC   A0A0G0K1L5;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Cell division protein FtsI, Peptidoglycan synthetase {ECO:0000313|EMBL:KKQ34556.1};
GN   ORFNames=US52_C0054G0003 {ECO:0000313|EMBL:KKQ34556.1};
OS   candidate division WS6 bacterium GW2011_GWA2_37_6.
OC   Bacteria; Candidatus Dojkabacteria.
OX   NCBI_TaxID=1619087 {ECO:0000313|EMBL:KKQ34556.1, ECO:0000313|Proteomes:UP000034852};
RN   [1] {ECO:0000313|EMBL:KKQ34556.1, ECO:0000313|Proteomes:UP000034852}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA   Wilkins M.J., Williams K.H., Banfield J.F.;
RT   "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT   radiation of phyla.";
RL   Nature 0:0-0(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKQ34556.1}.
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DR   EMBL; LBTH01000054; KKQ34556.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0G0K1L5; -.
DR   Proteomes; UP000034852; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE   4: Predicted;
KW   Cell cycle {ECO:0000313|EMBL:KKQ34556.1};
KW   Cell division {ECO:0000313|EMBL:KKQ34556.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          51..215
FT                   /note="Penicillin-binding protein dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF03717"
FT   DOMAIN          260..435
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   450 AA;  50899 MW;  2F1E437839E8F0C1 CRC64;
     MKSVSTSKLK ILLWFVYIFF ILNLIFLIRW QVFEHDRFIA LARERIVDNK VPSIRGDILA
     RDGSSLAYSE PRFNIIVYKT ELEFAEKYKK QTRDEFVSKV GKVLGIKEAT LTQMLENDKD
     WVKITEKITN DKKDELLSLK RDNASDQELE GIRIEYTSER IYPEHELACH AIGFVGKNDI
     GDDLGRAGLE HYWEGLLKEQ EGYNSSEVDS FGNLIALNNV SQIEAKRGAT IYTTIDKNIQ
     SIVQKNIQAA VKKYDAKSAT AIVMNPKTGE ILALANYPDF DPNDYEKVKD AQSFKNPAIS
     DPAELGSVGK AFTMSAALNE GKIQPNTQVT AGHSGCVTIK ENERDWKVCT YDKRPMGPMT
     ATQALVNSDN LALYEIMKLV GPEKFNEYLK AFGIGRRTDI DISGESNGEL KDVSEWTNVD
     SATYAYGHGY QMTEINETIS CFQSSRSRWY
//