ID A0A0G0M885_9BACT Unreviewed; 299 AA.
AC A0A0G0M885;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
GN ORFNames=UT20_C0007G0034 {ECO:0000313|EMBL:KKQ96550.1};
OS Candidatus Levybacteria bacterium GW2011_GWA1_39_11.
OC Bacteria; Candidatus Levybacteria.
OX NCBI_TaxID=1618453 {ECO:0000313|EMBL:KKQ96550.1, ECO:0000313|Proteomes:UP000034928};
RN [1] {ECO:0000313|EMBL:KKQ96550.1, ECO:0000313|Proteomes:UP000034928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC ChEBI:CHEBI:140347; EC=3.5.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00001526};
CC -!- SIMILARITY: Belongs to the class-A beta-lactamase family.
CC {ECO:0000256|ARBA:ARBA00009009}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKQ96550.1}.
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DR EMBL; LBVX01000007; KKQ96550.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0M885; -.
DR Proteomes; UP000034928; Unassembled WGS sequence.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF3; BETA-LACTAMASE2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251}.
FT DOMAIN 69..272
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
SQ SEQUENCE 299 AA; 33264 MW; 45DE1F69B3A89FA8 CRC64;
MNSREFLIVS LGSILFALSL FAIFPQKTST KILSPLSGNS NQGNTPIIRG GSLKEVVEKS
LLGTKGKYGI VIKNLKNGEA YLKNENEKFE PASLYKLWVL GTAFKLIKEG KLSKTEVLAR
DVKELNEMFQ IDEEETGQTE GTIQMTTSEA IDRMITASHN YAALLLVSRI RNSTISAFMK
EQNFKDSRLG SPPQTSARDM ALFFEKLYSG SMVDGNRSKE MLELLIRQEL NDRIPKYLPK
GIEVAHKTGE IGGFKHDAGI VFAKDPILIV ILSESNSPKG AAERIAELSR NIYGYFEDK
//
