ID A0A0G0WPE1_9BACT Unreviewed; 478 AA.
AC A0A0G0WPE1;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KKS14594.1};
GN ORFNames=UU71_C0022G0002 {ECO:0000313|EMBL:KKS14594.1};
OS Parcubacteria group bacterium GW2011_GWB1_41_6.
OC Bacteria.
OX NCBI_TaxID=1618869 {ECO:0000313|EMBL:KKS14594.1, ECO:0000313|Proteomes:UP000034062};
RN [1] {ECO:0000313|EMBL:KKS14594.1, ECO:0000313|Proteomes:UP000034062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKS14594.1}.
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DR EMBL; LCBR01000022; KKS14594.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G0WPE1; -.
DR STRING; 1618869.UU71_C0022G0002; -.
DR PATRIC; fig|1618869.3.peg.516; -.
DR Proteomes; UP000034062; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409:SF7; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE; 1.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485}.
FT DOMAIN 1..135
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 180..402
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 478 AA; 55694 MW; 3497512DDC85AB5F CRC64;
MITLLHINYS QDHSEKILPL GILSVGSALK KNGFAVNLIN INEKEINRTV EEIIKTNPDF
LGISVMTGTQ TKHSAELSKK IKQKSNIPIL WGGIHPSLLP KQCLEESYID FVAVGEGEET
IVEFAGKFLK GEELGSILGL GYKKEGQPVL NPQRPLIADL NKWRLDFSLL DLEKFIFPLD
KYKRVIAYKT SRGCPFQCAF CYNYEFNKAR WRAWSEEAVL EDINFLKEKY KIDAVKFYDD
NFFVDRKRAL SLLKKINLPS HLEIRIDFID EALVKELKDL KIFDMLIGIE SGSNRLLQLI
DKRFTVERLL EGVRVIADNN LHASYSLMVG LPTESRKEFK QTIDLMYKIY KIHPKAGFTL
GAYLPYPGSR LYEFGLKQGF KPPATTEKWG EIDRFRKNFS SPWVNVRKVW TIRECFKILS
WDFKPLKKWF EFRIKKNFYF LPWDIYLVER LAGVAIEEKG ILGKLLRRGY NFLRFRKI
//
