ID A0A0G1EBW8_9BACT Unreviewed; 1048 AA.
AC A0A0G1EBW8;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=beta-mannosidase {ECO:0000256|ARBA:ARBA00012754};
DE EC=3.2.1.25 {ECO:0000256|ARBA:ARBA00012754};
GN ORFNames=UV78_C0003G0011 {ECO:0000313|EMBL:KKT07561.1};
OS Parcubacteria group bacterium GW2011_GWA2_43_17.
OC Bacteria.
OX NCBI_TaxID=1618827 {ECO:0000313|EMBL:KKT07561.1, ECO:0000313|Proteomes:UP000033819};
RN [1] {ECO:0000313|EMBL:KKT07561.1, ECO:0000313|Proteomes:UP000033819}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-mannose residues
CC in beta-D-mannosides.; EC=3.2.1.25;
CC Evidence={ECO:0000256|ARBA:ARBA00000829};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKT07561.1}.
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DR EMBL; LCFU01000003; KKT07561.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1EBW8; -.
DR Proteomes; UP000033819; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR43730; BETA-MANNOSIDASE; 1.
DR PANTHER; PTHR43730:SF1; BETA-MANNOSIDASE; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 3.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 254..326
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 531..670
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 1048 AA; 120284 MW; 6810D3AFC88DB5ED CRC64;
MAKELDNMNA DIIDISEGWD LGWCKETKLN KWIQVFGFWK IEKGRLVGEG CSPHIFANIE
PENNYVWESI VCIDAMQGEL SVVVKRSLER FAYYDICFKP GSQIRARYVY SAVPDTILLE
NVGPVIESGK EYKVQIFVQD GIIKVRVDDE PVGEFKDTFL TGKNPGFHAS GNGVAYLRQI
KLTDIVTGNV IFEDDLKTNS LIKKVPVDLS ELISEEWVSA DIPGSVHSSL LKAGKIADPY
LGYNGPKQEW IDNQRWIYKS KFKVPVSWRG KNLRLLFEGV DYHGYFWLNG VLLGYHEGMF
GGPEYDISSL VDRNRENELV VCLLPSPSPA HSTVKPYILQ RWHFNMDILS IGLWRKVKLM
AFDNITLDSP QVVTRSISED KAILNISISV ANLAMYPFEV RGEFILQSPC KNVPDIVVEF
APGFFHGSMR VDRTMEVPNP QLWWPNGMGE QNIYKLTIVA NIYEPLKGTD PTGHAEMCIT
TGIRTLEMKP SPNINGKYKW IFCINGRPFF GKGSNWMPVD QMLRLSPEKY DRLLKLARES
NINILRPWGA GLLETEEFYD ACDRYGICVW QEFPLANGYF REIDKDVWRN TIIRNVVRLR
NRPSLVMWCG GNEFDPDHVD NKEIVDDLEN LCRELDMTRD FHRACPYGGD SHSYQVNWMA
NANYTFYTRD LSIAVTEYSM ASPPCMDTLK KIIPAEELNK WPPDSPENLS KVEYDKWGTA
VCRRESAFSM HDAHLSKIMG AMIPSISDCG IPGNWEEFIR YAQTEHGILT QFGIDFWRSR
WPYCTAVMSW VFNVVWPSAM SWEYVDWFGV PKASYYYQKR AFEPIHIGAV FEQLFWCPGS
TFRTKLYVAN ETLTKLKDVS IKVMLYNYSL ELLKEQTQKL DIPADDVKHC GFFEYEIPMV
SKEQVLFLCV DLLGADGHVL SRSQYTPRVG QPNIQMPYIT KGPWISDVKN FPTALESQYD
GDWTKLDDGT ITRTIAIKNI GDRPAYQVSI GVPDFEEFMR YSDNFFWLEA GEKRVVEIYV
LSGKQPEVEI SAWNAEKTTV KIISEKAK
//
