ID A0A0G1JDY4_9BACT Unreviewed; 696 AA.
AC A0A0G1JDY4;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=UW63_C0055G0003 {ECO:0000313|EMBL:KKT69530.1};
OS Candidatus Uhrbacteria bacterium GW2011_GWF2_44_350.
OC Bacteria; Candidatus Uhrbacteria.
OX NCBI_TaxID=1619000 {ECO:0000313|EMBL:KKT69530.1, ECO:0000313|Proteomes:UP000034154};
RN [1] {ECO:0000313|EMBL:KKT69530.1, ECO:0000313|Proteomes:UP000034154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC {ECO:0000256|ARBA:ARBA00009922}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKT69530.1}.
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DR EMBL; LCJB01000055; KKT69530.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1JDY4; -.
DR PATRIC; fig|1619000.3.peg.820; -.
DR Proteomes; UP000034154; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR CDD; cd18807; SF1_C_UvrD; 1.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF3; ATP-DEPENDENT HELICASE_DEOXYRIBONUCLEASE SUBUNIT B; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}.
FT DOMAIN 7..292
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 293..552
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT REGION 634..696
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 666..685
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 28..35
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 696 AA; 78005 MW; 2812BF40619C7457 CRC64;
MKIDYQKELN SEQLQVVLNG DGPCLVLAGA GSGKTRTVTY RVAYLLEQGI KPQEILLLTF
TNKAAKEMLT RVENLLGAEA RGIMGGTFHS TAARILRSYA NLVGRTSGFT ILDEDDSKSL
LKLCLKEAGV DSTHDKRYPS PSSFKSLWSY SRNSGLTLRD VLDRRTPALV GIAGNLEYVA
DLYEKRKHDS NAVDFDDLLL LFMHLLQNRP DVCERLSSQF RYVLVDEFQD TNFIQAKIVQ
MLSSVHRNLL VVGDDAQSIY SFRAAEIKNI LDFPKVYPAT KVFRLTSNYR SAPEILSLAN
ASIKNNRDQF EKPLRAMKES GQKPKLFSTA STFEEARRIA DEIGLLKNQG VPTTEIAVLF
RAAFHAQPLE FELMKRNVAY EFRGGMRFFE RAHIKDVTAH LRVLANLKDE AAWVRTLSLY
PGIGTTTAQK ILDQVKNFET LAEAVATDSV SPTRAASGWE ICRGVLKHML AATHPSDMIR
AVVAQGYRDY LEAEQPDFRD RLDDLEQFAV FAETSKDLHS FLDDVTLAEN YTAKQPMQDE
RLILSTIHQA KGLEWDAVFV IGLRDGGFPN PRAVAEGEIE EERRLFYVAT TRARKNLYLT
YPLSDGRSDD FSSGLPSLFV SELPRGVFVE ERRPVSGYPS SSSSSSHWGK QDDWADDEPT
IVLDSLGEPS ATSFSPPTNS KPKKSGFSFL RDVNEL
//
