ID A0A0G1MG25_9BACT Unreviewed; 876 AA.
AC A0A0G1MG25;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
GN ORFNames=UW75_C0008G0002 {ECO:0000313|EMBL:KKT79812.1};
OS Parcubacteria group bacterium GW2011_GWF2_44_8.
OC Bacteria.
OX NCBI_TaxID=1618971 {ECO:0000313|EMBL:KKT79812.1, ECO:0000313|Proteomes:UP000034896};
RN [1] {ECO:0000313|EMBL:KKT79812.1, ECO:0000313|Proteomes:UP000034896}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000256|RuleBase:RU004279}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|RuleBase:RU004279};
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000256|RuleBase:RU004279}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKT79812.1}.
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DR EMBL; LCJN01000008; KKT79812.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1MG25; -.
DR PATRIC; fig|1618971.3.peg.93; -.
DR Proteomes; UP000034896; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd01609; RNAP_beta'_N; 1.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 1.10.40.90; -; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 4.10.860.120; RNA polymerase II, clamp domain; 1.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 2.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR012754; DNA-dir_RpoC_beta_prime_bact.
DR InterPro; IPR000722; RNA_pol_asu.
DR InterPro; IPR006592; RNA_pol_N.
DR InterPro; IPR007080; RNA_pol_Rpb1_1.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR044893; RNA_pol_Rpb1_clamp_domain.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR NCBIfam; TIGR02386; rpoC_TIGR; 1.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF54; DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA; 1.
DR Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR Pfam; PF00623; RNA_pol_Rpb1_2; 2.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR SMART; SM00663; RPOLA_N; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU004279};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|RuleBase:RU004279};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004279};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004279}.
FT DOMAIN 276..561
FT /note="RNA polymerase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00663"
SQ SEQUENCE 876 AA; 98472 MW; 27EEEFFED4D7E3A9 CRC64;
MSSTQQPFAK HTPATPNFTE ISLKLASPET ILEWSHGEVT KPETINYRTQ RPEKHGLFDE
RIFGPVEDYE CSCKKYRGIR YKGIVCEKCG VEVTRAIVRR ERMGHIDLCI PVSHIWFLRG
VPSRIAMILG ITASSVEKVI YFAGYIVTKV SEDDRGRLLK ELDTEFKTKY KALQNEDARE
ALKTRADDMK KEIENINPGV VLDEASFHRF SIKYSTLFEA RIGAEAIFEL FKQVNLQDLL
KRLEKERETA GAMERAKLDK RLSLVRGMVN AGVRPEWMFL TRIPVIPPAI RPMVALEGGR
HASSDLNDLY RRVINRNNRL KKLIDIMAPD VILRNEKRIL QEAVDALIDN SIRHGGGAYS
AMSQAQRRPL KSLSDYLKSK QGYFRQNLLG KRVDYSGRSV IVIGPELALD QCGLPKHMAL
ELFRPFVIAQ LLKQELAYNI RGAGRLIEDG VPEVWAILEN VIKHKHVLLN RAPTLHRQGI
QAFRPVLIEG NAIQVHPLVC RAFNADFDGD QMAVHVPLSE EAQMEAREII SANKNILKPG
SAEPVVSEKL LDMALGAYWM TKVIPGALGE GKYFSSPNDA INAYDYGVID FRAKVHVLAT
ETEKYAQYEG KIFETTVGRL IFNSVLPSDH DFINDIIVQR TLFAVIIDII DARGPEAVPP
IVDKLKKLGL KYATLSGTTW GIDEVQVPKE KPAIIEKARV EERGILAAFE EGLISRDERR
RMIVEVWHRA KTEIERVLPD TLDENGSAYE MWKSGARGSL GQIAQMAGMK GLIVNTRGET
VEFPILSSMK EGMSPIEYFT TTHGSRKGLA DTALQTAKAG YLTRRLFVVA QDAIVTESDC
KTKAGVRIGR VSASGIFFLK MLSTLRVELS SLRVTY
//
