ID A0A0G1MNQ6_9BACT Unreviewed; 1136 AA.
AC A0A0G1MNQ6;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
DE Flags: Fragment;
GN ORFNames=UX13_C0032G0001 {ECO:0000313|EMBL:KKU09737.1};
OS Candidatus Woesebacteria bacterium GW2011_GWB1_45_5.
OC Bacteria; Candidatus Woesebacteria.
OX NCBI_TaxID=1618581 {ECO:0000313|EMBL:KKU09737.1, ECO:0000313|Proteomes:UP000034329};
RN [1] {ECO:0000313|EMBL:KKU09737.1, ECO:0000313|Proteomes:UP000034329}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000256|RuleBase:RU004279}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|RuleBase:RU004279};
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000256|RuleBase:RU004279}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKU09737.1}.
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DR EMBL; LCLA01000032; KKU09737.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1MNQ6; -.
DR PATRIC; fig|1618581.3.peg.512; -.
DR Proteomes; UP000034329; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd02655; RNAP_beta'_C; 1.
DR CDD; cd01609; RNAP_beta'_N; 1.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 1.10.150.390; -; 1.
DR Gene3D; 1.10.1790.20; -; 1.
DR Gene3D; 1.10.40.90; -; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 4.10.860.120; RNA polymerase II, clamp domain; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR000722; RNA_pol_asu.
DR InterPro; IPR006592; RNA_pol_N.
DR InterPro; IPR007080; RNA_pol_Rpb1_1.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR044893; RNA_pol_Rpb1_clamp_domain.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF54; DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA; 1.
DR Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR Pfam; PF00623; RNA_pol_Rpb1_2; 2.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 2.
DR SMART; SM00663; RPOLA_N; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU004279};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|RuleBase:RU004279};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004279};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004279}.
FT DOMAIN 250..519
FT /note="RNA polymerase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00663"
FT COILED 86..148
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KKU09737.1"
SQ SEQUENCE 1136 AA; 125284 MW; 4E3DB95678260377 CRC64;
KGVICDKCGV EVTQSRVRRE RMGHISLASP VAHVWFFKGA PSKISLILGV APRGIEQVVY
FARYLVIEVD DVKKKDALKN IEKARNERLD EVVQSFKSRK DALKAEEKEA KDKIQNKIKD
KEQASLATAE IELNLRKKEA AINEEEKATV AKTEQLFENI NGVVKNLRPL SIISEEEYDE
LYQHDAVDFF VAKMGADAVL AAVEKINLEE LAKILRDEID SIKGGSSKYV KLVKRLKLVE
GLKRAKINPS WMVLRVLPVL PPDLRPMVQL SGGRFATSDL NDLYRRVINR NNRLKHLISL
GAPEIILRNE KRMLQEAVDS LIDASQRKAT RKSRGRQPLR SLSDMLRGKQ GRFRQNLLGK
RVDYSGRSVI IVGPELKLTQ CGLPKDMALE MFKPFVLREM IARGIAPNVK SAKNMLDRRP
PEVFDILEEI TKDHPVLLNR APTLHKLSIQ AFYPVLIEGS AIRIHPAVCS GFNADFDGDQ
MAVHVPLSAR AIEEAKKLML PENNLLKSSD GSPTIFADTS EAVFANQAGK LEIRQKIKVM
IGKEIVETTV GRILLNEVLP ENFDFVNEGA TSSVIKGLFV KAYATVSRER VVQLVDDIKD
LGFFGGTISG ISFGIFDAKV YPGKAKVLEE ANMRVGEIED NFAQGLITAE EKRRLVQEVW
IEVSEDLADK TWEQMEETNP IRVVIDAKVG RASRDQVKQL AAIRGLVVDP LGKIVELPIK
SNFREGLSVF EYVTSSRGSR KGLTDTAIKT ADAGYLTRRL VDVAHDVLIR LEDCGSKEGY
AIRKDVRSQV FAARILGRIA AQDVRVKEGK TVIVAAGDMI DEEKAKKIDG SAVTEVVVRS
PLACEARYGI CAKCYGWDLG TKNMVEMGVP VGVVAAQSIG EPGTQLTLRT KHAAGVVGVD
VTQGLPRVEE LVESRIPKVA SALSGISGKV RVGESDEGWK VTVVGKGTPK EEKEYIIPKT
LSLAVSDGEA ISAGTPLAKG PLDIKDILSI RGLRAAQEYL VHEIQKVYES QGIPINDKHF
EVIVRKMSDE VRIVTTGDTP FLPGELTSRA NFEEENEKVL AAGGEPASAQ QVVLGITRRA
LYTDSWLSAA SFEQTTDVLT EASLLGREDK LVGLKENVII GRLIPVSPER AALPLG
//
