ID A0A0G1U677_9BACT Unreviewed; 306 AA.
AC A0A0G1U677;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
GN ORFNames=UY21_C0032G0005 {ECO:0000313|EMBL:KKU89584.1};
OS Microgenomates group bacterium GW2011_GWA1_48_10.
OC Bacteria.
OX NCBI_TaxID=1618496 {ECO:0000313|EMBL:KKU89584.1, ECO:0000313|Proteomes:UP000034718};
RN [1] {ECO:0000313|EMBL:KKU89584.1, ECO:0000313|Proteomes:UP000034718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC ChEBI:CHEBI:140347; EC=3.5.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00001526};
CC -!- SIMILARITY: Belongs to the class-A beta-lactamase family.
CC {ECO:0000256|ARBA:ARBA00009009}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKU89584.1}.
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DR EMBL; LCPD01000032; KKU89584.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1U677; -.
DR Proteomes; UP000034718; Unassembled WGS sequence.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF3; BETA-LACTAMASE2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251}.
FT DOMAIN 72..273
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
SQ SEQUENCE 306 AA; 33699 MW; D022D41033B29466 CRC64;
MPANLLSKIK GPLVAIGLLV IGLLLSSLNN KTYFDQFFFG AENKTPAPSI TNLAIQNYLQ
AETGKLPGNY CVYIKDLKRG ATYKVNANQP LATASIYKLA VMYKTYDAIN RGELKKEDVL
TEDESTLDQI LKPEADTNTS GTVSYMVADA LRAMITVSDN YSALLLADKL GWKNIDDFLK
QQKIEGFDLV GGQQPTATAE AVAILLERIF RNTAVNSQSS EEMKGLLLAQ QVNDRIPKYL
PKDTKVAHKT GELDNFRHDA GIIYGKNSTY IFVFLSETPA PGDAVENIAN LSQKMYDALE
NPNSLK
//
