ID A0A0G1W9E3_9BACT Unreviewed; 559 AA.
AC A0A0G1W9E3;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Transporter, CPA2 family {ECO:0000313|EMBL:KKW15421.1};
GN ORFNames=UY55_C0001G0175 {ECO:0000313|EMBL:KKW15421.1};
OS Candidatus Jorgensenbacteria bacterium GW2011_GWB1_50_10.
OC Bacteria; Candidatus Jorgensenbacteria.
OX NCBI_TaxID=1618665 {ECO:0000313|EMBL:KKW15421.1, ECO:0000313|Proteomes:UP000034224};
RN [1] {ECO:0000313|EMBL:KKW15421.1, ECO:0000313|Proteomes:UP000034224}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Brown C.T., Hug L.A., Thomas B.C., Sharon I., Castelle C.J., Singh A.,
RA Wilkins M.J., Williams K.H., Banfield J.F.;
RT "rRNA introns, odd ribosomes, and small enigmatic genomes across a large
RT radiation of phyla.";
RL Nature 0:0-0(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC transporter (TC 2.A.37) family. {ECO:0000256|ARBA:ARBA00005551}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKW15421.1}.
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DR EMBL; LCQK01000001; KKW15421.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G1W9E3; -.
DR STRING; 1618665.UY55_C0001G0175; -.
DR PATRIC; fig|1618665.3.peg.178; -.
DR Proteomes; UP000034224; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR42751:SF3; NA(+)_H(+) ANTIPORTER; 1.
DR PANTHER; PTHR42751; SODIUM/HYDROGEN EXCHANGER FAMILY/TRKA DOMAIN PROTEIN; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..22
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 29..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 406..526
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
SQ SEQUENCE 559 AA; 61603 MW; 183B8191FB826454 CRC64;
MSIGVLELAA VVGFAAVLGI AAKALRQPVI LAYLAAGVFI AYFGFFNLAS ESTFKIFSDL
GIMFLLFLVG LEINYSSLRI AGKPSVVVGL GQVIFAFVIG YFIALQFGFE QLEAAYISVA
LTFSSTIIVV KLLSDKKDLN SLYGRISVGM MLVQDFIAIF ILILLSGVEA GKGVEILPIT
IAVLKGLVLV VVVFWLGKRF FPWLFEKIAR SEELLFLTST AWVFLFAAAL SELGFSIEIA
GLLAGLALAN SSENFQIASR IRPLRDFFIM IFFVILGASL IFTGVKDLGL PAVVLSLFVL
IGNPLIVLII MGLMGYRRRT SFLTGITTAQ ISEFSMILGA VGLKLGHFGE NVLGLITAVG
VVTITLSTYM IIYSRGLYKF LSWPLRLFEK KNAKEEEIRE EIYEKPIVLV GCGRTGASIA
YNLPKEKLLI VDFNPEEIES LRRRGYEALF GDIADSEIFE KANFPQAALA ISTSSDFEDN
MVFLEEIKKL PRRPKIILRA ETEREARAFY AAGADYVLLP HFTSGQYLGK TLAIDPEMEI
LDSLRERDLA LMQKVNHAV
//
