ID A0A0G2HKS8_9SYNE Unreviewed; 1707 AA.
AC A0A0G2HKS8;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Helicase {ECO:0000313|EMBL:KKZ12043.1};
GN ORFNames=TE42_06020 {ECO:0000313|EMBL:KKZ12043.1};
OS Candidatus Synechococcus spongiarum SP3.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC Synechococcus.
OX NCBI_TaxID=1604020 {ECO:0000313|EMBL:KKZ12043.1, ECO:0000313|Proteomes:UP000035067};
RN [1] {ECO:0000313|EMBL:KKZ12043.1, ECO:0000313|Proteomes:UP000035067}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SP3 {ECO:0000313|EMBL:KKZ12043.1};
RA Burgsdorf I., Slaby B.M., Handley K.M., Haber M., Blom J., Marshall C.W.,
RA Gilbert J.A., Hentschel U., Steindler L.;
RT "Lifestyle Evolution in Cyanobacterial Symbionts of Sponges.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKZ12043.1}.
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DR EMBL; JXQG01000031; KKZ12043.1; -; Genomic_DNA.
DR PATRIC; fig|1604020.3.peg.866; -.
DR Proteomes; UP000035067; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF13245; AAA_19; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50206; RHODANESE_3; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}.
FT DOMAIN 297..474
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 507..654
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 521..555
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
FT DOMAIN 1083..1299
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 1104..1111
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1707 AA; 191368 MW; DA6D22190CCB3D27 CRC64;
MSFPLRCLSL DLEVDQKTRR ILAFGAVRSD TGEGCCGGGS RAELSRLDTL AEGVDALLGH
NLIAFDIPHL AAVMPGLRLL QLPLVDTLRL SPLAFPRNPY HHLVKHYQAG GLQRGQINHP
ELDARIALEL FEDECKDLPR AAPELLSAWH WLSTPKPKGV DRALDVLFSW LRGGAPRPAT
VEGRQAIGQF LQGRACVNRG REAVNGAPQS GWGLSYVLAW LSVAGDNSVM PPWVRHQFPE
AGRWVHQLRD LACADPACDW CREHHDARKA LKRWFDFDNF RPEPADDGGC PLQQTIVECV
MGGGHGLGIL PTGTGKSLCY QLPALSRYDK TGALTVVISP LVALMADQVA GLEERGIGSC
FTINGLLSLP ERADVLDKVR LGDAGILLIS PEQLRSRSLR QALDQRQIGG WVLDEAHCLC
HWGHDFRTDY RYVGRFIKEK AGSGLVPPVL CLTATAKPDV IKEIKGYFHD KLNIDLKVFD
GGASRTNLVF EVMPTTGAEK FARIHHVLRE FLPLDVPGGA IIYCATRRRS EEVAQYLQAK
ELAVAHFHGG LPPETKKDVQ QRFIRGGCRA IAATNAFGMG IDKQDVRLVI HADIPGSLEN
YLQEAGRAGR DREPARCVLL YTPEDVEQQF KLSARSRLTQ AEIQSILRAL HNLSRKKRFK
SEVVATAGEI LRGDEDRGFQ RDAVTDDTRV RTALTWLEES ALLTREENVV QVFPSSLRVH
SLKEARQRLD RVPTMTEARR KQLLKITERL INAPPDEGVT TDELMGVGRL SPEGVRAALH
DLESLGIANN DTVLTAFVHA DVARSSRKRL EEARALETAL IAHMREEAPD QGKGDTSFLH
VRRVAQVLRD QHLPDPLPER LWRIVRGIAC DGRGEDGAGG SWSVRKRDME TVRVTLQREW
SALERTVRRR HTGASRLLDH LLSCLPRGIQ GVDLLAETTM GRLLEAIRSD LAVNSQVQNP
QKLLDRALMW LHDLDIIRLN KGLTVFRPAM TIRMKQAERR RGFARVDFEL LALHYREQVL
QIHVMAEFAQ RGLADMREAW LLSMDYFKLP EDQFLARWLP GRNKEIRRQT TPASWRTIVE
SLKNPVQQRI VADDQEQTNV LVLAGPGSGK TQVLVHRIAY LIRMRRENPR GIVALAYNRH
AAVQIRRRLE ALLGHDARGV TVLTCHGLAM RLAGASFSGR LERPDNGAFQ EVIRRAVDVL
RGKDLPPAEA DDRREQLLAG FRWILVDEYQ DIDAHQYDLI SALAGRNLEE DAGKLTLFAV
GDDDQNIYAF KGASVAFIRQ FEEDYNSRPS YLTANYRSTA HIIAAANAVI ASARQRMKAE
HPIHRDPARE EDPPGGRWEA MDPVARGRVQ ILPVGASSLS QAQVVMGELL RLRELAPRWD
WSRCAVVARE WNALVPVRAF CKDRGIPVQM GNEAVPGVWR LRETQALVAW LRNRTSPMVA
GDALNTWIED QPAGPWYDLL RQAIEDYRLE TGAGETPVEH CIEWLAEWSR DVRQRQQGLL
LLTAHRTKGL ELDHVAVLDG DWGRVQQGED PDAERRLYYV AMTRARHTLL LARFRQTHHL
QDGLADHPAV LWREPVPPQP PSPAMTHHHV RAEHKHVDLG FAGRCSSTDP VHAAIAALSP
GDPLKTHIDS RGHWKLLDAT GRVVGRLAQA FQPLPGMRCR SATVLAVIVW SRTTSEPQYQ
DRIQCDFWEV VVPELVFEPE RRQGQGS
//
