ID   A0A0G2I1F5_9EURO        Unreviewed;       889 AA.
AC   A0A0G2I1F5;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   08-NOV-2023, entry version 28.
DE   RecName: Full=UNC-45/Cro1/She4 central domain-containing protein {ECO:0000259|Pfam:PF11701};
GN   ORFNames=EMCG_01719 {ECO:0000313|EMBL:KKZ63965.1};
OS   Emmonsia crescens UAMH 3008.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emmonsia.
OX   NCBI_TaxID=1247875 {ECO:0000313|EMBL:KKZ63965.1, ECO:0000313|Proteomes:UP000034164};
RN   [1] {ECO:0000313|Proteomes:UP000034164}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 3008 {ECO:0000313|Proteomes:UP000034164};
RX   PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA   Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA   Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA   Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA   Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA   Clay O.K., Klein B.S., Cuomo C.A.;
RT   "The dynamic genome and transcriptome of the human fungal pathogen
RT   Blastomyces and close relative Emmonsia.";
RL   PLoS Genet. 11:E1005493-E1005493(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKZ63965.1}.
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DR   EMBL; LCZI01000886; KKZ63965.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0G2I1F5; -.
DR   VEuPathDB; FungiDB:EMCG_01719; -.
DR   Proteomes; UP000034164; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.100; -; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR024660; UCS_central_dom.
DR   PANTHER; PTHR45994; FI21225P1; 1.
DR   PANTHER; PTHR45994:SF1; FI21225P1; 1.
DR   Pfam; PF11701; UNC45-central; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        281..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          225..376
FT                   /note="UNC-45/Cro1/She4 central"
FT                   /evidence="ECO:0000259|Pfam:PF11701"
SQ   SEQUENCE   889 AA;  95836 MW;  8BB6DBA7B3B169AD CRC64;
     MVQSASDDRA VQLAREAVEL VDAGHREAAS RNLREAISLA PENEEVKSAF KKISEDEETN
     HPLVSLCRRY VTHKDEEAGR EAALRLRVDG LQPPPEVAVD SLNLILSCPA ASLSNTQDDI
     ISALVRNSAH IRRHFAAQLQ LSVTQFFDEI YDRGDGAVVC LDTVVLDTAL WQSEKVRNHC
     KNELFQLFIA KLMESGHDLD GRSLKGIARL LAVDAENLQH LVDEDCFDAI LSSLDLRLPI
     DVRSQATLAT AKYLEAAGEN GQTFFTKILT ARVARQRNDD YIIAFSAAAA VFPIIPSITA
     TLFLTDGFVQ SLVVLLEQKR KNSTVERAVL ELFNAACIDK QCREAIDKYC GEWLSYTLSS
     GTEENSELAA VTLAKIRASE NGAHPKPTVA SGVRGEESFG SSHDLVERFK SLLAKRPQKG
     DFHHLVEGLA FSSVKPDVKE QLASKESAFP SDLVAILKNN TTDSSLIYGG LMIIHNLTKY
     LPNISEEQKK ISELRSYANA SSKPATSDPL DDDHHVKERC GTIINAGIMP LLTDCNKANT
     TSNSIQDLTS KILLSLSKIP QTRGKLAQQG AVKLLLSLLS YRTDNNTNYR ENDEPTQNAA
     HALARILISV NPAHVFSSSG FPQITTAIRP LIHLLQPLSS TTTNPSPSPS LSTETPRDLL
     PSFESLLALT NLASTSTPNA SSSSSPSAAT TITRLAFPTI EDLLLSSNTY LQRAASELTC
     NLMTCPDGVA KFADGTPRAA QRLHILLALA DVRDLATRRA AGGALAALTE FEGVVEAVLE
     REGGVEVLLG MCREGAGEGG SGDGDGEGDG DGGMEMIHRG LVCVRNMGCC EGEVGRRARR
     VLKERGAVEV LRGCLVGGVG AAADGGRGRG MGEEVLRCGV EGLRVLVES
//