ID A0A0G3AEB8_9ACTN Unreviewed; 551 AA.
AC A0A0G3AEB8;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Long-chain fatty acid--CoA ligase {ECO:0000313|EMBL:AKJ12168.1};
GN ORFNames=ABB07_19625 {ECO:0000313|EMBL:AKJ12168.1};
OS Streptomyces incarnatus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=665007 {ECO:0000313|EMBL:AKJ12168.1, ECO:0000313|Proteomes:UP000035366};
RN [1] {ECO:0000313|EMBL:AKJ12168.1, ECO:0000313|Proteomes:UP000035366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL8089 {ECO:0000313|Proteomes:UP000035366};
RX PubMed=26159526;
RA Oshima K., Hattori M., Shimizu H., Fukuda K., Nemoto M., Inagaki K.,
RA Tamura T.;
RT "Draft Genome Sequence of Streptomyces incarnatus NRRL8089, which Produces
RT the Nucleoside Antibiotic Sinefungin.";
RL Genome Announc. 3:e00715-e00715(2015).
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DR EMBL; CP011497; AKJ12168.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G3AEB8; -.
DR STRING; 665007.ABB07_19625; -.
DR PATRIC; fig|665007.5.peg.4202; -.
DR Proteomes; UP000035366; Chromosome.
DR GO; GO:0016877; F:ligase activity, forming carbon-sulfur bonds; IEA:UniProt.
DR CDD; cd12119; ttLC_FACS_AlkK_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF11; MEDIUM-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:AKJ12168.1}.
FT DOMAIN 36..399
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 454..531
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 551 AA; 59901 MW; 08B3D6F012A272E2 CRC64;
MLSTMQDVPL LISRILTHGS TVHGSSRVTT WTGESGPHRR TFAEVGARAA QLAHALRDEL
GVTGDDRVAT LMWNNAEHVE AYFAIPSMGA VLHTLNLRLP AEQLVWIVNH AADRVIILNG
SLIPMLAPLL SKLPTVEHVV VSGPGDRSPL AGAGAQVHEY EELIADRATA YDWPELDERR
AAAMCYTSGT TGDPKGVVYS HRSIYLHSMQ VNMAQSMGLT DQDTSLVVVP QFHVNAWGLP
HATFMTGVNL LMPDRFLQPA PLAEMIESEK PTHAAAVPTI WQGLLAELTA RPRDVTSLTQ
VTIGGAACPP SLMAAFDKLG MRVCHAWGMT ETSPLGTVSR PPAHVVGTDE EFAYRLTQGR
FPAGVEARLT GPGGERLPWD GESAGELEVR GPWIAGAYYN GPDAEPLRPT DKFSEDGWLK
TGDVGTISPD GFLTLTDRAK DVIKSGGEWI SSVELENALM SHPDVTEAAV VAVPDEKWGE
RPLATVVLKE GATADFEALR SFLAEEARIA RWQLPERWTI VESVPKTSVG KFDKKVLRRR
YADGELDVTR L
//
