ID   A0A0G3AQJ3_9ACTN        Unreviewed;       507 AA.
AC   A0A0G3AQJ3;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Peptidase C69 {ECO:0000313|EMBL:AKJ14025.1};
GN   ORFNames=ABB07_29465 {ECO:0000313|EMBL:AKJ14025.1};
OS   Streptomyces incarnatus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=665007 {ECO:0000313|EMBL:AKJ14025.1, ECO:0000313|Proteomes:UP000035366};
RN   [1] {ECO:0000313|EMBL:AKJ14025.1, ECO:0000313|Proteomes:UP000035366}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL8089 {ECO:0000313|Proteomes:UP000035366};
RX   PubMed=26159526;
RA   Oshima K., Hattori M., Shimizu H., Fukuda K., Nemoto M., Inagaki K.,
RA   Tamura T.;
RT   "Draft Genome Sequence of Streptomyces incarnatus NRRL8089, which Produces
RT   the Nucleoside Antibiotic Sinefungin.";
RL   Genome Announc. 3:e00715-e00715(2015).
CC   -!- SIMILARITY: Belongs to the peptidase U62 family.
CC       {ECO:0000256|ARBA:ARBA00005836}.
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DR   EMBL; CP011497; AKJ14025.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0G3AQJ3; -.
DR   STRING; 665007.ABB07_29465; -.
DR   PATRIC; fig|665007.5.peg.6247; -.
DR   Proteomes; UP000035366; Chromosome.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR   InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR   InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR   InterPro; IPR035068; TldD/PmbA_N.
DR   InterPro; IPR036059; TldD/PmbA_sf.
DR   PANTHER; PTHR30624:SF10; CONSERVED PROTEIN; 1.
DR   PANTHER; PTHR30624; UNCHARACTERIZED PROTEIN TLDD AND PMBA; 1.
DR   Pfam; PF01523; PmbA_TldD_1st; 1.
DR   Pfam; PF19289; PmbA_TldD_3rd; 1.
DR   SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670}.
FT   DOMAIN          33..97
FT                   /note="Metalloprotease TldD/E N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01523"
FT   DOMAIN          253..498
FT                   /note="Metalloprotease TldD/E C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19289"
SQ   SEQUENCE   507 AA;  54921 MW;  B34DBD0993E975FD CRC64;
     MPHSIDEAFT ALPLRSLADA ALARARALGA EHADFRFERV RSASWRLRDA RPAGSSDTTD
     LGYAVRVVHG GSWGFASGVD LTMDAAARVA SQAVAMAKLS AQVIKAAGAD ERVELADEPV
     HADRTWVSSY EIDPFSVPDE EKAGLLAEWS ARLLAADGVD HVDASLLTVH ENKFYADTAG
     TVTTQQRVRL HPQLTAVSVD ESSGEFDSMR TLAPPVGRGW EYLTGTGWDW DDELARIPEL
     LAEKMRAPSV EPGLYDLVVD PSNLWLTIHE SIGHATELDR ALGYEAAYAG TSFATFDQLG
     KLRYGSQLMN VTGDRTAEHG LATIGYDDEG VEGQSWDLVK DGTLVGYQLD RRIARLTGFD
     RSNGCAYADS PAHVPVQRMA NVSLRPDPAG LSTEDLIGGV DRGIYVVGDR SWSIDMQRYN
     FQFTGQRFFR IENGRITGQL KDVAYQANTT DFWGSMTAVG GPQTYVLGGA FNCGKAQPGQ
     VASVSHGCPS ALFRAVNILN TTQEAGR
//