ID A0A0G4FD52_VITBC Unreviewed; 1085 AA.
AC A0A0G4FD52;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Helicase ATP-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=Vbra_9046 {ECO:0000313|EMBL:CEM11161.1};
OS Vitrella brassicaformis (strain CCMP3155).
OC Eukaryota; Sar; Alveolata; Colpodellida; Vitrellaceae; Vitrella.
OX NCBI_TaxID=1169540 {ECO:0000313|EMBL:CEM11161.1, ECO:0000313|Proteomes:UP000041254};
RN [1] {ECO:0000313|EMBL:CEM11161.1, ECO:0000313|Proteomes:UP000041254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhu J., Qi W., Song R.;
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CDMY01000410; CEM11161.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G4FD52; -.
DR STRING; 1169540.A0A0G4FD52; -.
DR VEuPathDB; CryptoDB:Vbra_9046; -.
DR InParanoid; A0A0G4FD52; -.
DR OMA; IMLKNYN; -.
DR OrthoDB; 1352at2759; -.
DR PhylomeDB; A0A0G4FD52; -.
DR Proteomes; UP000041254; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR CDD; cd18024; DEXHc_Mtr4-like; 1.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.30; -; 1.
DR Gene3D; 2.40.30.300; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR048392; MTR4-like_stalk.
DR InterPro; IPR025696; MTR4_beta-barrel.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016438; SKI2-like.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF7; EXOSOME RNA HELICASE MTR4; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF21408; MTR4-like_stalk; 1.
DR Pfam; PF13234; MTR4_beta-barrel; 1.
DR PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000041254}.
FT DOMAIN 154..310
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 381..585
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 709..732
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..48
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 714..732
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1085 AA; 121552 MW; 48FEAB4FB470B0C1 CRC64;
MDDVDDLFAA FDQKDEPAAR DKPPPRQLKR AAEKPSEGRP DQGDQQEQAP KRPRVQPQAS
DGPQAAAAAA PTANGGAAAA AEDGGMAGGG GGGGSDDAGG GAGAKVVIEK YSEKPNCMHY
CVRPSTYERK PMPTVSTPAH TYPFILDPFQ ATSNQCLEAR ESVLVSAHTS AGKTCVAEYA
IAMGLRDNQR VIYTSPIKAL SNQKYRDLSE KFKDVGLLTG DVSLNAHASV VVMTTEILRS
MLYRGSELMR EMAWVIFDEI HYMRDRERGV VWEETLILLP DTVKLVFLSA TIPNSLEFAE
WIANIKHQPC HVVYTDYRPV PLQHYMFPAG GDGIYLVMDE KGEFKESRFT EAVASIGKDI
EDQKMLTKKQ LAKNRDRNRS DLEKIVKMCH EKSYTPAIIF SFSKRDVEGN AVAMKKIDLL
GDDDKRMVEQ IFDNAMKTLA DEDRALPQIL YIKPLLMRGI GIHHGGLLPI IKEVIEILFQ
EGLLKVLFST ETFSMGVNMP AKTVVFTSIK KWDGQEFRWI NSGEYIQMSG RAGRRGLDDR
GFTILMFDEQ VEPETAKGMF TGQALRLDSQ FHLGYNMLLN LMRVEGADPE YMIQRSFYQF
QRDKRALGIQ ELCKKLKEEA EGMEDIVPLI EMPEGVALPD IDVNRSVAEY HKLTERQNAL
RETYRSIVML PENISRYMQT GRMVHVVDQD GVDWGWGIVA GAVRRPHKTA AAAARDSSGS
SNHQQQQQQS SSGEFIVDVL LECDLRSTQT VSAVRKPTPA RAGQERVVEV MPVSDSCIHG
VAKMRANLGD INYKEASGRA HAKITMEKIR ERFDGSPPLL DPISEMGLDG ITLQPTIDKL
KQCESDIASH PLHNHPLLDK LLDKYRERLD REEQVRGLET ELAGHRYLVM KDDLRAMRKV
LKRLQYVDKD GVVTLKGRVA CEITTTEELV VTELLFRNTF QTMEADHMVA TLSALCFDEK
IEDHVDLHPE LAKGFDQIKE VAKMTAEVSA ESKLPIKVDE YLEKFKPNLM PVVLRWMRGE
SFKDVIDGTG LFEGSVIRGM RRLEELLRQL AAASKAIGND EMEAKMREGV TKLRRGIVFA
ASLYL
//
