ID A0A0G4LTQ0_9PEZI Unreviewed; 740 AA.
AC A0A0G4LTQ0;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Calpain catalytic domain-containing protein {ECO:0000259|PROSITE:PS50203};
GN ORFNames=BN1708_004013 {ECO:0000313|EMBL:CRK25461.1};
OS Verticillium longisporum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=100787 {ECO:0000313|EMBL:CRK25461.1, ECO:0000313|Proteomes:UP000044602};
RN [1] {ECO:0000313|EMBL:CRK25461.1, ECO:0000313|Proteomes:UP000044602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VL1 {ECO:0000313|EMBL:CRK25461.1};
RA Wang D.B., Wang M.;
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C2 family. PalB/RIM13 subfamily.
CC {ECO:0000256|ARBA:ARBA00010193}.
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DR EMBL; CVQH01018890; CRK25461.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G4LTQ0; -.
DR STRING; 100787.A0A0G4LTQ0; -.
DR OrthoDB; 230045at2759; -.
DR Proteomes; UP000044602; Unassembled WGS sequence.
DR GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.380; -; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR022682; Calpain_domain_III.
DR InterPro; IPR022683; Calpain_III.
DR InterPro; IPR036213; Calpain_III_sf.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001300; Peptidase_C2_calpain_cat.
DR PANTHER; PTHR46143; CALPAIN-7; 1.
DR PANTHER; PTHR46143:SF1; CALPAIN-7; 1.
DR Pfam; PF01067; Calpain_III; 1.
DR Pfam; PF00648; Peptidase_C2; 1.
DR SMART; SM00720; calpain_III; 1.
DR SMART; SM00230; CysPc; 1.
DR SUPFAM; SSF49758; Calpain large subunit, middle domain (domain III); 2.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS50203; CALPAIN_CAT; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00239}; Protease {ECO:0000256|PROSITE-ProRule:PRU00239};
KW Reference proteome {ECO:0000313|Proteomes:UP000044602};
KW Thiol protease {ECO:0000256|PROSITE-ProRule:PRU00239}.
FT DOMAIN 22..322
FT /note="Calpain catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50203"
FT ACT_SITE 62
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00239"
FT ACT_SITE 236
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00239"
FT ACT_SITE 256
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00239"
SQ SEQUENCE 740 AA; 81770 MW; 10CAF9A3C4F39708 CRC64;
MTCRDHTEYA MSHQQNDILG GWERPAALVG SLLHTDEPFD GTAALMAASG DCDLVQDITT
DCSVVASLCA AMDVLVAKSR GKPLLSRLMF PYDHTNDRPK LSQSGKYIFR MHFNGCFREV
VIDDRLPVSR AGIDRNLFVV DRRNPDSLWP ALMEKAYLKV RGGYDFPGSN SGTDLWVLTG
WIPEQLFLQR SSEDVDLNQT WSRMLQCHQE GDLIITLGTG RLTHTEEDAL GLVGEHDYAV
LKLEEVNGTR RLLVKNPWCD GLVWKGAELR EHSRSTANPP SIGSSGGAHL EMTSTAPSRG
TFWISLEEVA QNFESMYLNW NPSCFGRRQD HHFTWQVPAM SWSGTFAHNP QYSICSSTSD
TVWILLSRHF ADAELSIARN QRLGSLASIA RRLGYTSISI FDNGGKRVQE IGGALYRGPY
VDSPQTLAKF ALDAGKTYTV VMAHEELPLN EYSCTFSFFS AANLKIGPAE EVMRHYRELS
SSWTRRSAGG NASSPTYSAN PQFSITVSRS TPLSILLTTG SRDIAIHTDL VWSSGKRVSS
IGRKDVVASS GDYRCGSAHS HVANLEPGTY VIVCSTFEPG QLSDFAIRIG TMVECAVRPV
PGDGAGLLCT RLPALDFAAG EERKRASITA PRLTKAYASA RCPVLSDENG QHISHAAIRI
VVMYGRGPNA SIHAISCEGE FRDPTTAVRT PEFDLEPDRV RHEDLWIVIE QLGSHRAWSG
IEVEILGDNL IRYSPWEDLD
//
