ID   A0A0G4M9C0_9PEZI        Unreviewed;      4794 AA.
AC   A0A0G4M9C0;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Midasin {ECO:0000256|PIRNR:PIRNR010340};
GN   ORFNames=BN1708_005195 {ECO:0000313|EMBL:CRK30555.1};
OS   Verticillium longisporum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX   NCBI_TaxID=100787 {ECO:0000313|EMBL:CRK30555.1, ECO:0000313|Proteomes:UP000044602};
RN   [1] {ECO:0000313|EMBL:CRK30555.1, ECO:0000313|Proteomes:UP000044602}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VL1 {ECO:0000313|EMBL:CRK30555.1};
RA   Wang D.B., Wang M.;
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Nuclear chaperone required for maturation and nuclear export
CC       of pre-60S ribosome subunits. {ECO:0000256|PIRNR:PIRNR010340}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR010340}.
CC   -!- SIMILARITY: Belongs to the midasin family.
CC       {ECO:0000256|PIRNR:PIRNR010340}.
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DR   EMBL; CVQH01021418; CRK30555.1; -; Genomic_DNA.
DR   STRING; 100787.A0A0G4M9C0; -.
DR   OrthoDB; 1221059at2759; -.
DR   Proteomes; UP000044602; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   CDD; cd00009; AAA; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 6.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR040848; AAA_lid_7.
DR   InterPro; IPR011704; ATPase_dyneun-rel_AAA.
DR   InterPro; IPR048617; MDN1_AAA_lid_4.
DR   InterPro; IPR012099; Midasin.
DR   InterPro; IPR041190; Midasin_AAA_lid_5.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR48103:SF2; MIDASIN; 1.
DR   PANTHER; PTHR48103; MIDASIN-RELATED; 1.
DR   Pfam; PF07728; AAA_5; 8.
DR   Pfam; PF17865; AAA_lid_5; 1.
DR   Pfam; PF17867; AAA_lid_7; 3.
DR   Pfam; PF21108; MDN1_4th; 1.
DR   PIRSF; PIRSF010340; Midasin; 1.
DR   SMART; SM00382; AAA; 6.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 6.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR010340};
KW   Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|PIRNR:PIRNR010340};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|PIRNR:PIRNR010340};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR010340};
KW   Reference proteome {ECO:0000313|Proteomes:UP000044602}.
FT   DOMAIN          299..542
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          633..903
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          1082..1227
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          1371..1583
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          1751..1942
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          2061..2295
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   REGION          752..772
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          4092..4680
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        4137..4152
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        4153..4204
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        4223..4237
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        4249..4276
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        4302..4323
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        4324..4354
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        4355..4392
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        4393..4407
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        4408..4431
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        4438..4467
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        4475..4544
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        4573..4587
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        4588..4606
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        4607..4639
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        4640..4660
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   4794 AA;  531592 MW;  8B29826D906D49CE CRC64;
     MATVDISPQR AALLDDAIVL EQLPQEILAV IRDDTSTNLL DVLSQAALIP QLTSRLFVHF
     EHVFPDLCAR WILNPTDAKT QTDVLASFAR VLRFAPYLST FLRHYMSSVS SPTSNKPLGL
     QQLDFVSLQN LQQDELLRLL LAVWRLISFD ASAYSILVSP AQMQSLFAHE HLAVRYLCIR
     IFCLQVHAAD AKREALIREH VGASAISGDF DGQHVDFGFL PLHEHARVEN LDALRRERNE
     RALKDDVPAI PPQALTPLVA CYGQTILPRP SAPSHNTSSL VPTTTTSNNL ESLANLLKDR
     KPILLHGLPG SGKTSVIHEF AKEFGKHSGM VTLHINEQTD AKMLVGLYAA DSKPGSFSWR
     PGVLTTAVRE GRWVLIEDLD RAPNEVISTL LPLIERGQLL IPSRGETIKA SSEFRLFATV
     RTTKGMHGRE TLPNLLGLRF WQQLSIQIPS EAEFLDIIVG TYPILRRFAP EIMAVFRRLT
     NSVSGASRGS FNRSLLDRQP SSRDLLRWCR RLASLLADAN CTTGDEPISD TTRDQMFMEA
     VDCFVSRIPD AKARQHITFQ IAEEWHMAKE RVEHYLEASI PQLEDGPDHF RIGRVKLRKK
     KDRSGKIVKS KRPFANTTHA KKLLEQAAVA VKSGEPVLLV GETGIGKTTV IQQLADTLGH
     KLIAVNLSQQ SEVGDLLGGF KPVNVRSLAV PLMEEFEDLF AATGISATKN QAYLELLGKT
     FAKGDWSRVS RQWRQAPKMF IKIVEELTRR ENEQREARNG EDQPTKRRKT ESKLQRLLDL
     KPRWDAFTRS LDQFEIQMSG GSGAFAFSFV EGNIVKAARN GDWVLLDEIN LASPDTLESI
     ADLLTGPAET PSILLSETGE IQRIKAHPNF RMFGAMNPAT DIGKRDLPIG IRSRFTEIYV
     DSPDRDVKDL LTIVKTYLKG SGTRDDKAAD DIARLYLDTK LRAEEKSLVD GANEVPHFSL
     RTLTRVLSYV NHIAPFYGLR RALYEGFSMG FLTLLNRDSE KLLMPLIDHR LFGQISNPQS
     LLSKPPTHPD DGKKYVRFVN KAKNRHYWLS QGALEPQERS DYIITPYVER NLLNLVRATS
     TRKFPILIQG PTSAGKTSMI EYLANFTGNK FVRINNHEHT DLQEYLGTYA SDSNGKLRFQ
     EGLLVQAMRQ GHWIVLDELN LAPTDVLEAL NRLLDDNREL LIPETQEIVR PHENFMLFST
     QNPPGLYGGR KALSRAFRNR FLELHYDDIP EDELEYILQQ RSRNTAPSDC KRIVTVYKEL
     SRLRQTSRMF EQKDSFATLR DLFRWTQRSA EDREQIAING FMLLAERVRV DEERIAVKEI
     IEKVFKVKID PEQLYSTMFT GKGKSGENSQ GVVWTGAMRR LYTLVDYALR NNEPVLLVGD
     TGCGKTTVCQ MLAEALGKEL HIVNAHQNTE TGDLIGSQRP VRNRGAISDT LKSELATLLT
     RVGQPSSGSF DELMQAYREL PADVLSTVDA AVLESITALE TKSKALFEWS DGSLVNSMKS
     GDFFLLDEIS LADDSVLERL NSVLEPGRTL LLAEKGIDNS FVTASNGFQF LATMNPGGDF
     GKKELSPALR NRFTEIWVPS LSDREDVLQI VRSKLDTTLR NFGSTIVHFS AWFGETFRSS
     HSAAYSIRDI LLWVKFINHF GSVNPNFAVV HGAATVFVDT LGANPSALLA MDPKSMEAQR
     QQCLDKLSEL LKCDATKIYR SQPEVTMDAN TLSLGQFEIA REPGVAIDPT IAFNAPTTRL
     NLMRVLRSLQ MQKPILLEGS PGVGKTTLVA ALASTCGRPL TRINLSDQTD LMDLFGTDMP
     VEGAEAGNFA WRDAPFLQAM QRGEWVLLDE MNLASQSVLE GLNACLDHRG EVYISELDQV
     FHKHPDFRLF AAQNPHHQGG GRKGLPSSFV NRFIVVYADV LTEEDLLLIA GHSFPDIPWD
     VTRGVIRFIT KLDHQIVIEK SFGLQGGPWE FNLRDILRWL NLLASKDPLL STGTVDDFLG
     LIVRQRFRSN LDRKEVDNLF ASIFGRQPHD HSLYHDISTA FSQVGNALIA RNQLSQPSKL
     PAINIVPRLS EIESVMICVK QNIPCIIGGP SGSGKSALLQ HVAAVAGKSL VVFPLNADID
     TMDLVGGFEQ ADPLRELNAA LRALHETLEV SVLSQVPAQV PHEALSLLHA LDGYHGNLDA
     LEAIAASVQT VLSEVSPTTE IAALLTNVFE LLQKPLEATD PRFEWLDGVI VKALQTGQWL
     VLDNANLCNA SVLDRLNSLL EPNGFLSINE HCGPDGEPRM IKPHPEFRIF LTVDSRYGEL
     SRAMRNRAIE IHLSELPEGM KVSHQTGADV DSNLRRLQMS RDISAATLQS ESYVDVSSLT
     LDNLSVQDTA LVPRYSGALT QTLMGLPSEA LEKYRSNLEE ISNYLTTDEA AAVRQATLEI
     YATLPNDSHS ELQHAQPLST LQNAPIARLL QRTSGDLAFW LNCCFQFILE LQRCQSTLKA
     QVGRAKAGKL ASLNRLQRSV VSDRIAAVAK DSTASVSKFL TKVLQAALKF LQDSVKDAGD
     WKDQCRIIRH MLDFWWRTFG LVAQQHFEEA RFQAHLGHGV KSLQTALSQV QESSIHGALA
     SGFLQAIQED FNAGFKLKTG LSMEPLWNLL KPAAILSAEA LESHRDIERL AIRFDALRWK
     VRTSISDLAS AMSTLVTADQ VVRSNASLTS QLIADLKKEI DTLEAGVSSA SREVSPFFTA
     EYETLRQALV LQSISYGTTL PAEHMVLAVA SDLPTFDQSR FSNTLGSAQK LLSTGLLASR
     DAKTHVWNGK LATSLLAKSN SIKNASLDSL RMLEAELPLL GRTLARSAPD ITSNSIQALN
     NSLKHLISEI VAAHSVGAGA LVDNVFTHAY SNADLTATTP EQLKAVVLKI RVAFPEEWPA
     QLVTVFKDHL LPSIVAVAAS DKHAACLDSA NTAGDRLVVA FSSVAWVQFS VGCIKLYVPD
     KAFDPQLRPQ YEMEVHDNTK AVLDHRLASL LEFETNFTGQ KTSLRAQLVQ EEIEALGAAP
     PASQILYRPA KSELGGIQAD FNNILKSVVD MDVASTHVAH TLTDTTGLNE EMDLVRXNVG
     QLIDRLSSRF DAYQDMVLPA VNILHCLQLG LSLNKGLASL QDQLPTAPFM GVLPFLGGTL
     PKPNATSLPT RSLNFLNYMG LVVSVEGLPR LDAPGRQALF SSFHGFFDDW NKKLEADRKT
     EQENTSLYKF RGSFEDEEEQ DEEEFNELFP TFDDEEDKKP AVQRQKVRNL SVKMAELHRN
     IFSQPEEASE SLRKACAAIS HELALEASQR VAVGQDLNQK MLPSAMWSLY EELSALNVSV
     QTDNYNFYSD ANLPMVRQLI SLVNKVELRF HELQQVDEIG FMQPLADVLT ACETLLSLVH
     TEPLASILPK LEHLHMIVYE WQHGGYAPAI YGAPALYTAL TDMIISWRRE ELKTWARLFD
     LEAQKCRDDA NSWFFMAYQV VVAVPLTLAD KADELQEYAV SLVKELGNYF STSIVGQFSG
     RLALLRQMQK HLELLTVDYP SLAVVRDATQ NFITFYSRFE AVIDEAIGRG RAPIEKNVKN
     TVLMTSWKDT NINALRESAR KSHRSLFRLV RKFRSVLGQP AAPVIEQGLP DKEPITDSGA
     ASIIITPSVD KKALARCKKA APQWLKQNKR LNNMGTTLSV MASVTKYSSG TTAASQEAVA
     FVESLKASIA ELRKETPPFL NDENKDQVKH LKTRKRNLFA DVLKALRKMG VRHNLGTEDL
     NRQKTTATVL GSTRAYARES EGQDAAEYYF HKAIDIAAKV RPAGLDHHSE LTGAEVTRSV
     GFMEGFVQLL LQQRASLVPA STSVGPLKEV IGSVRQLSMY WGDKSLTVQR QSSNLLKAVD
     WIVPVLRFGV QLVEVHGKLA TTDHSQVVQT LQNRLDGFAA SLTKRDTSST IPERLQTSEQ
     KAIDEESQLS LQALGKELDD MASAHPNLAF VLQQIKAWTT VSRQDYDDDN DALESPPSLD
     SFSAEVSNVC NSVLVAMQVH KKAATGLPTT SDGAAWLVDA SAASAAMLKG LHIHGVTDAI
     RRCLSALKRL DLDAPALRSA ATSMLGAVLP ILDQYAATCQ QSVAQLRDLH EATGRMTHFL
     GLTFSQLTAK GFCTPQDKSD ETQGDAGKLE SGTGLGDGEG AEDISKDIQP DENLSELAQE
     SNKERNSEME DEKDAVDMAD EDMEGDMGSV DGADDEENGD DKDDGDEDGD DNDMEEEAGE
     VDDLDPTTVD EKMWDGENED EAEKEQQGEK AKGQQKDEQT AAADAQPNDE SGEMEEPGDE
     QGDEGEDEDP AAEQEDVQFQ EDIKQDQNVQ QEDALALPDD MELDLKDEES GSDDDDLDDM
     SDSGEPKDDL PDLPEKHESD IEDDQQPERG QDPEQADEAP EEEMDMGGNE IDDEPKAEEE
     QDGEDPDAEP EQPDEPEDKR QDADQDTANA DTENAAPSDV KSGGQDQNAD SMDVENEPDD
     SAAQRDEGAA GEGAAKQEAD AGKKGAVSRS DDQAQPTEQQ EDEAAREEPR QDPFKKLGDA
     LERWHRQQTE IKEAEQKQEE GEAKQPQQDT DDMAAKEFQH MLDDETAPDA QALGAASDDQ
     VQPIDDAMAI DEEKEDPSSR VMPESEQEPE QQDEAAGDEM DTDDPEDKKD GPERDDGRSG
     VKTRQGAFDR EATPEDADAV KMEDADEDED EDEDEADNNM DEASAQLSET HLTGDPERPL
     RDFDEAMQLW TGFQTRTNAL SQSLTSQLRL ILNPSQSTKL SGYDAGRAEI IHLVRRDAHP
     VLRRVVVVVR RVGAAEARAQ ARVHRGSRCR VRQQALGAGE PEHGAVVEGR WRPG
//