ID A0A0G4MS23_9PEZI Unreviewed; 970 AA.
AC A0A0G4MS23;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Fe2OG dioxygenase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BN1708_007286 {ECO:0000313|EMBL:CRK37031.1};
OS Verticillium longisporum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=100787 {ECO:0000313|EMBL:CRK37031.1, ECO:0000313|Proteomes:UP000044602};
RN [1] {ECO:0000313|EMBL:CRK37031.1, ECO:0000313|Proteomes:UP000044602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VL1 {ECO:0000313|EMBL:CRK37031.1};
RA Wang D.B., Wang M.;
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the isochorismatase family.
CC {ECO:0000256|ARBA:ARBA00006336}.
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DR EMBL; CVQH01024527; CRK37031.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0G4MS23; -.
DR STRING; 100787.A0A0G4MS23; -.
DR OrthoDB; 1644896at2759; -.
DR Proteomes; UP000044602; Unassembled WGS sequence.
DR GO; GO:0051213; F:dioxygenase activity; IEA:InterPro.
DR GO; GO:0006307; P:DNA dealkylation involved in DNA repair; IEA:InterPro.
DR GO; GO:0035552; P:oxidative single-stranded DNA demethylation; IEA:InterPro.
DR CDD; cd00431; cysteine_hydrolases; 1.
DR Gene3D; 1.20.1050.10; -; 1.
DR Gene3D; 2.60.120.590; Alpha-ketoglutarate-dependent dioxygenase AlkB-like; 1.
DR Gene3D; 3.40.50.850; Isochorismatase-like; 1.
DR InterPro; IPR027450; AlkB-like.
DR InterPro; IPR037151; AlkB-like_sf.
DR InterPro; IPR032854; ALKBH3.
DR InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR004046; GST_C.
DR InterPro; IPR000868; Isochorismatase-like.
DR InterPro; IPR036380; Isochorismatase-like_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR PANTHER; PTHR31212; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3; 1.
DR PANTHER; PTHR31212:SF5; ISOCHORISMATASE FAMILY PROTEIN FAMILY (AFU_ORTHOLOGUE AFUA_3G14500); 1.
DR Pfam; PF13532; 2OG-FeII_Oxy_2; 1.
DR Pfam; PF00043; GST_C; 1.
DR Pfam; PF00857; Isochorismatase; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR SUPFAM; SSF52499; Isochorismatase-like hydrolases; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
DR PROSITE; PS50405; GST_CTER; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000044602}.
FT DOMAIN 534..658
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
FT DOMAIN 796..944
FT /note="GST C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50405"
FT REGION 242..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 413..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 583..607
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 934..970
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..267
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..376
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 583..604
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 970 AA; 104721 MW; 4432F447607256FE CRC64;
MFPFDQSALP SLPKRKALLV IDFQSDFLDA EAPLRVTRPH GFVEKTVQFA DAFRKLGDVV
WVCSEFDKVR PIAGEQILAT DETPKPSAVT AAGAASGRRR GPKVELIPAP VADTDPEAFL
SAGGIPCVRS PSGSQIPGNV KDASLKRDVT FIKSHYSAFK SGQLLHLLRG KFITHIFIAG
SLMNIGVFAT ALDAAMYGYD ITIVDDCCGY RSQVRQGNAI QSVIDVTGCE VDSSSTVLEQ
LQAKPPSAKP AVASPATSSS SATTANKKVG GLAGARTPPI PGRVRAKAST SDLHEKLAAL
KISSTPGGRI EPESDPNSLA LEVDPDAQPS SHDLNSPRRK PSSADDRDPI LDLEAIRNKY
RTSKDTRTDT SQARKLKQPR LADMAAPNKP GTVVPARVGK GLEPKIIEPE VTVPATAPSD
SASASKDEHD PATADTLPET SEPLCEGDTV IIHNVLPPNL LEGVFEKLKD EVGWQTMSHQ
GGEVPRKVAV QGLVAEDGSM PVYRHPADES PPLFPFTKTV LEIKAVVEEK LGHPLNHVLI
QFYRDGNDYI SEHSDKTLDI VKGSYIVNVS LGAERTMIFR TKRDAKDPSK KTDDIPEGAK
RKTTRKQLPH NSLCRMGLVT NMRWLHAIRQ DKRAERDKAA PELAFAGGRI SLTFRQIGTF
LDRDGTLIWG QGATGKTRAD AHPVVNGQGP EAVAMLRAFG TENHASEFDW DAHYGQGFDV
LHMSSAPRLF FSADAVVNMR VQLALAEHGI LFAKGRMPPS FDWKEGKAEA AAPAVISSAL
ESLSIKYVDN DADRLTAQGD MAILLYLDGL HGKRSEPSKG QARILTRFQQ GLALLDKWRA
IRSQETDDVT VKQPAKPLKR ELTVWNDYAA EDESIAGEAV SIADFAVWPV LHDIVQTLGE
GVLNGTKSLK KYYQAFSERE ATIKVLAVDP PAVAAAETQP KPESQSAAEA KAEGGTNPVA
EGDAGVKAEE
//
