ID A0A0G9F8I8_LACPN Unreviewed; 622 AA.
AC A0A0G9F8I8;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Chaperone protein DnaK {ECO:0000256|ARBA:ARBA00014415, ECO:0000256|HAMAP-Rule:MF_00332};
DE AltName: Full=HSP70 {ECO:0000256|HAMAP-Rule:MF_00332};
DE AltName: Full=Heat shock 70 kDa protein {ECO:0000256|HAMAP-Rule:MF_00332};
DE AltName: Full=Heat shock protein 70 {ECO:0000256|HAMAP-Rule:MF_00332};
GN Name=dnaK {ECO:0000256|HAMAP-Rule:MF_00332,
GN ECO:0000313|EMBL:AOB23717.1};
GN Synonyms=dnaJ {ECO:0000313|EMBL:APD01312.1};
GN ORFNames=ASV54_08090 {ECO:0000313|EMBL:APD01312.1}, AVR83_12520
GN {ECO:0000313|EMBL:AOB23717.1}, C7M36_02594
GN {ECO:0000313|EMBL:QHM38281.1}, LPJSA22_01870
GN {ECO:0000313|EMBL:ODO61891.1}, SN35N_2985
GN {ECO:0000313|EMBL:BBA83364.1};
OS Lactiplantibacillus plantarum (Lactobacillus plantarum).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactiplantibacillus.
OX NCBI_TaxID=1590 {ECO:0000313|EMBL:ODO61891.1, ECO:0000313|Proteomes:UP000094892};
RN [1] {ECO:0000313|Proteomes:UP000183026}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MF1298 {ECO:0000313|Proteomes:UP000183026};
RA McLeod A., Rud I., Axelsson L.;
RT "Genome sequence of Lactobacillus plantarum MF1298, a candidate probiotic
RT associated with unfavorable effect.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AOB23717.1, ECO:0000313|Proteomes:UP000093296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DF {ECO:0000313|EMBL:AOB23717.1,
RC ECO:0000313|Proteomes:UP000093296};
RA Petkau K., Fast D., Duggal A., Foley E.;
RT "Comparative evaluation of the genomes of common bacterial members of the
RT Drosophila intestinal community.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ODO61891.1, ECO:0000313|Proteomes:UP000094892}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JSA22 {ECO:0000313|EMBL:ODO61891.1,
RC ECO:0000313|Proteomes:UP000094892};
RA Choi H.S.;
RT "Genome sequencing of Lactobacillus plantarum JSA22, isolated from
RT fermented soybean paste.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:BBA83364.1, ECO:0000313|Proteomes:UP000269784}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SN35N {ECO:0000313|EMBL:BBA83364.1,
RC ECO:0000313|Proteomes:UP000269784};
RX PubMed=29607926; DOI=.1248/bpb.b17-00840;
RA Noda M., Shiraga M., Kumagai T., Danshiitsoodol N., Sugiyama M.;
RT "Characterization of the SN35N Strain-Specific Exopolysaccharide Encoded in
RT the Whole Circular Genome of a Plant-Derived Lactobacillus plantarum.";
RL Biol. Pharm. Bull. 41:536-545(2018).
RN [5] {ECO:0000313|EMBL:QHM38281.1, ECO:0000313|Proteomes:UP000464882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRCM101167 {ECO:0000313|EMBL:QHM38281.1,
RC ECO:0000313|Proteomes:UP000464882};
RA Jeong D.-Y.;
RT "Lactobacillus plantatrum SRCM101167 having anti-virus activity species
RT isolated from Korea kimchi.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:APD01312.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MF1298 {ECO:0000313|EMBL:APD01312.1};
RA McLeod A., Fagerlund A., Rud I., Axelsson L.;
RT "Genome sequence of Lactobacillus plantarum MF1298, a candidate probiotic
RT associated with unfavorable effect.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Acts as a chaperone. {ECO:0000256|ARBA:ARBA00002290,
CC ECO:0000256|HAMAP-Rule:MF_00332}.
CC -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000256|HAMAP-
CC Rule:MF_00332}.
CC -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|HAMAP-Rule:MF_00332,
CC ECO:0000256|RuleBase:RU003322}.
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DR EMBL; CP013753; AOB23717.1; -; Genomic_DNA.
DR EMBL; CP013149; APD01312.1; -; Genomic_DNA.
DR EMBL; AP018405; BBA83364.1; -; Genomic_DNA.
DR EMBL; MCOL01000001; ODO61891.1; -; Genomic_DNA.
DR EMBL; CP028334; QHM38281.1; -; Genomic_DNA.
DR RefSeq; WP_003640711.1; NZ_WYDR01000010.1.
DR GeneID; 77218349; -.
DR PATRIC; fig|1590.142.peg.1852; -.
DR OMA; MGTDWKI; -.
DR Proteomes; UP000093296; Chromosome.
DR Proteomes; UP000094892; Unassembled WGS sequence.
DR Proteomes; UP000183026; Chromosome.
DR Proteomes; UP000269784; Chromosome.
DR Proteomes; UP000464882; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR CDD; cd10234; HSPA9-Ssq1-like_NBD; 1.
DR Gene3D; 1.20.1270.10; -; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR HAMAP; MF_00332; DnaK; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR012725; Chaperone_DnaK.
DR InterPro; IPR018181; Heat_shock_70_CS.
DR InterPro; IPR029048; HSP70_C_sf.
DR InterPro; IPR029047; HSP70_peptide-bd_sf.
DR InterPro; IPR013126; Hsp_70_fam.
DR NCBIfam; TIGR02350; prok_dnaK; 1.
DR PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR PANTHER; PTHR19375:SF184; STRESS-70 PROTEIN, MITOCHONDRIAL; 1.
DR Pfam; PF00012; HSP70; 1.
DR PRINTS; PR00301; HEATSHOCK70.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF100934; Heat shock protein 70kD (HSP70), C-terminal subdomain; 1.
DR SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR PROSITE; PS00297; HSP70_1; 1.
DR PROSITE; PS00329; HSP70_2; 1.
DR PROSITE; PS01036; HSP70_3; 1.
PE 2: Evidence at transcript level;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00332};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|HAMAP-Rule:MF_00332};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00332};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|HAMAP-
KW Rule:MF_00332};
KW Stress response {ECO:0000256|ARBA:ARBA00023016, ECO:0000256|HAMAP-
KW Rule:MF_00332}.
FT REGION 527..563
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 579..622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 225..252
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 579..603
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..622
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 176
FT /note="Phosphothreonine; by autocatalysis"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00332"
SQ SEQUENCE 622 AA; 66731 MW; 2436925123969521 CRC64;
MASNKIIGID LGTTNSAVAV LEGNEPKIIT TPEGGRTVPS VVAFKDGETQ VGEVAKRQAI
TNPNTVASIK RHMGEAGYKV SIEGKDYTPQ QISAMILQYI KGFAEDYLGD TVEKAVVTVP
AYFNDAQRQA TKDAGKIAGL NIERIINEPT AAALAYGLDK TDKDEKILVY DLGGGTFDVS
ILELGDGVFE VLSTNGDTHL GGDDFDQKII DWLVDGFKAD NGVDLSKDKM ALQRLKDAAE
KAKKDLSGVS EAQISLPFIS AGASGPLHLE TTLTRAKFNE LTADLVEKTR IPVENALKDA
DLSASDLDVV ILNGGSTRIP AVQEAVEKWT GKESNHSINP DEAVALGAAV QGGVITGDVK
DVVLLDVTPL SLGIETMGGV FTKLIDRNTT IPTSKSQVFS TAADNQPAVD IHVLQGERPM
AADNKTLGRF QLTDIPAAPR GVPQIEVKFD IDKNGIVNVS AKDMGTNKEQ KITIKSSSGL
SDDEIDQMVK EAKENEEADK KRKEEVDLKN EVDQLIFTTD KTLKDLEGKV SEDEVKKAKD
ARDALKKAQD DNNIDEMKAK KDDLNKIVQD LSVKLYQQAQ EAQGAQGGAD SNAAGNADSA
KGSDDNTVDG DFEDLDKDKD KK
//
