ID A0A0G9F8K6_LACPN Unreviewed; 282 AA.
AC A0A0G9F8K6;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Probable cell wall amidase lytH {ECO:0000256|ARBA:ARBA00018811, ECO:0000256|PIRNR:PIRNR037730};
DE EC=3.5.1.- {ECO:0000256|PIRNR:PIRNR037730};
GN Name=amiA {ECO:0000313|EMBL:ODO61869.1};
GN Synonyms=lytC {ECO:0000313|EMBL:QHM48465.1}, lytH
GN {ECO:0000313|EMBL:BBA83383.1};
GN ORFNames=ASV54_07980 {ECO:0000313|EMBL:APD01290.1}, C7M40_00389
GN {ECO:0000313|EMBL:QHM48465.1}, LPJSA22_01848
GN {ECO:0000313|EMBL:ODO61869.1}, LpLQ80_08600
GN {ECO:0000313|EMBL:AWI40579.1}, SN35N_3004
GN {ECO:0000313|EMBL:BBA83383.1};
OS Lactiplantibacillus plantarum (Lactobacillus plantarum).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactiplantibacillus.
OX NCBI_TaxID=1590 {ECO:0000313|EMBL:ODO61869.1, ECO:0000313|Proteomes:UP000094892};
RN [1] {ECO:0000313|Proteomes:UP000183026}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MF1298 {ECO:0000313|Proteomes:UP000183026};
RA McLeod A., Rud I., Axelsson L.;
RT "Genome sequence of Lactobacillus plantarum MF1298, a candidate probiotic
RT associated with unfavorable effect.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ODO61869.1, ECO:0000313|Proteomes:UP000094892}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JSA22 {ECO:0000313|EMBL:ODO61869.1,
RC ECO:0000313|Proteomes:UP000094892};
RA Choi H.S.;
RT "Genome sequencing of Lactobacillus plantarum JSA22, isolated from
RT fermented soybean paste.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:BBA83383.1, ECO:0000313|Proteomes:UP000269784}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SN35N {ECO:0000313|EMBL:BBA83383.1,
RC ECO:0000313|Proteomes:UP000269784};
RX PubMed=29607926; DOI=.1248/bpb.b17-00840;
RA Noda M., Shiraga M., Kumagai T., Danshiitsoodol N., Sugiyama M.;
RT "Characterization of the SN35N Strain-Specific Exopolysaccharide Encoded in
RT the Whole Circular Genome of a Plant-Derived Lactobacillus plantarum.";
RL Biol. Pharm. Bull. 41:536-545(2018).
RN [4] {ECO:0000313|EMBL:QHM48465.1, ECO:0000313|Proteomes:UP000465032}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRCM101518 {ECO:0000313|EMBL:QHM48465.1,
RC ECO:0000313|Proteomes:UP000465032};
RA Jeong D.-Y.;
RT "Lactobacillus plantatrum SRCM101518 having antimicrbial activity species
RT isolated from Korea kimchi.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:AWI40579.1, ECO:0000313|Proteomes:UP000244922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LQ80 {ECO:0000313|EMBL:AWI40579.1,
RC ECO:0000313|Proteomes:UP000244922};
RA Moriya N., Nakano K., Shiroma A., Shinzato M., Ashimine N., Minami M.,
RA Tamotsu H., Shimoji M., Nakanishi T., Ohki S., Teruya K., Satou K.,
RA Hirano T., Hagi T., Kobayashi M., Nomura M., Kimoto H.N., Tajima K.,
RA Cai Y., Suzuki C.;
RT "Complete Genome Sequence of Lactobacillus plantarum Strain LQ80 Selected
RT for Preparation of Fermented Liquid Feed for Pig.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:APD01290.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MF1298 {ECO:0000313|EMBL:APD01290.1};
RA McLeod A., Fagerlund A., Rud I., Axelsson L.;
RT "Genome sequence of Lactobacillus plantarum MF1298, a candidate probiotic
RT associated with unfavorable effect.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probably involved in cell-wall metabolism.
CC {ECO:0000256|PIRNR:PIRNR037730}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613,
CC ECO:0000256|PIRNR:PIRNR037730}.
CC -!- SIMILARITY: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.
CC {ECO:0000256|ARBA:ARBA00010860, ECO:0000256|PIRNR:PIRNR037730}.
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DR EMBL; CP013149; APD01290.1; -; Genomic_DNA.
DR EMBL; CP028977; AWI40579.1; -; Genomic_DNA.
DR EMBL; AP018405; BBA83383.1; -; Genomic_DNA.
DR EMBL; MCOL01000001; ODO61869.1; -; Genomic_DNA.
DR EMBL; CP028241; QHM48465.1; -; Genomic_DNA.
DR RefSeq; WP_003640692.1; NZ_WYDR01000010.1.
DR GeneID; 77218330; -.
DR PATRIC; fig|1590.142.peg.1830; -.
DR OMA; WHTNLNI; -.
DR Proteomes; UP000094892; Unassembled WGS sequence.
DR Proteomes; UP000183026; Chromosome.
DR Proteomes; UP000244922; Chromosome.
DR Proteomes; UP000269784; Chromosome.
DR Proteomes; UP000465032; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
DR CDD; cd02696; MurNAc-LAA; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 3.40.630.40; Zn-dependent exopeptidases; 1.
DR InterPro; IPR017273; LytH.
DR InterPro; IPR002508; MurNAc-LAA_cat.
DR InterPro; IPR003646; SH3-like_bac-type.
DR PANTHER; PTHR30404; N-ACETYLMURAMOYL-L-ALANINE AMIDASE; 1.
DR PANTHER; PTHR30404:SF0; N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIC; 1.
DR Pfam; PF01520; Amidase_3; 1.
DR Pfam; PF08239; SH3_3; 1.
DR PIRSF; PIRSF037730; CWA_LytH_prd; 1.
DR SMART; SM00646; Ami_3; 1.
DR SMART; SM00287; SH3b; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS51781; SH3B; 1.
PE 3: Inferred from homology;
KW Cell wall biogenesis/degradation {ECO:0000256|PIRNR:PIRNR037730};
KW Hydrolase {ECO:0000256|PIRNR:PIRNR037730, ECO:0000313|EMBL:ODO61869.1};
KW Ligase {ECO:0000313|EMBL:APD01290.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Secreted {ECO:0000256|ARBA:ARBA00022525, ECO:0000256|PIRNR:PIRNR037730};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..93
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
SQ SEQUENCE 282 AA; 30967 MW; 62C7B09C406185C9 CRC64;
MQVLKQFWRQ ITVTVIFIGL VIGFVVLLAT NNTATVNIAN VNIRSGPGMS YAIEDATSKG
TKVHIMKRKN NWLYVRYADH KFGWIASWLV NEHNSQLTKT TKISEATIVL DPGHGGSDSG
ALSSKGKMEK TYTLRVAKAV AKKLRAAGAH VVLTRDSDEY VGLSARPAIA NKLHADAFIS
FHFDSSPEKN TASGITTYYY HKSTSLALAK ALNNNVSTLP IPSKGTDFGD FLVIRDNSRP
SVLMELGYIN DKSDFKTISS KKYPQEVAHA VYAGLSTYFA NQ
//
