ID A0A0H2LVL4_VARPD Unreviewed; 516 AA.
AC A0A0H2LVL4;
DT 16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT 16-SEP-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=HTH-type transcriptional regulator NorG {ECO:0000313|EMBL:KLN54298.1};
GN Name=norG3 {ECO:0000313|EMBL:KLN54298.1};
GN ORFNames=VPARA_46470 {ECO:0000313|EMBL:KLN54298.1};
OS Variovorax paradoxus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=34073 {ECO:0000313|EMBL:KLN54298.1, ECO:0000313|Proteomes:UP000035170};
RN [1] {ECO:0000313|EMBL:KLN54298.1, ECO:0000313|Proteomes:UP000035170}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TBEA6 {ECO:0000313|EMBL:KLN54298.1,
RC ECO:0000313|Proteomes:UP000035170};
RA Poehlein A., Schuldes J., Wuebbeler J.H., Hiessl S., Steinbuechel A.,
RA Daniel R.;
RT "Genome sequence of Variovorax paradoxus TBEA6.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLN54298.1}.
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DR EMBL; JZWI01000025; KLN54298.1; -; Genomic_DNA.
DR RefSeq; WP_047786170.1; NZ_JZWI01000025.1.
DR AlphaFoldDB; A0A0H2LVL4; -.
DR PATRIC; fig|34073.19.peg.4751; -.
DR Proteomes; UP000035170; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF2; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000035170};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..72
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
FT REGION 487..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 516 AA; 56421 MW; E88C9B7D3EE88557 CRC64;
MDSLPLYRQL AAHYVDAIHT GSLKQGDKLP SLRSLMRLHG ISLSTALQLC RTMESDGWVE
ARDRSGYFVR RPRRLAIAPM EEPPAGVPPD PAQYVGIHAK VSDFVARRRQ LPEKLNFSIA
RGAPELYPAE ALRNAMTRML RQQPDMLTVA APLKGHRQFR EVLAQRSLRV GMAISPEDIL
VTNGCIEALN LALRAVAQPG DTVAVESPTF YGLLQVLESL GMRALEIPTS PQTGLSIEAL
ELAIRTYDNI KAVVVVPHLQ NPLGSVMPDA HKARLAQLCE RHGIPLIEDD TYSELVDAPT
PPRALKSWDA GGNVIHCASL HKILAPGLRL GWITAGRWHA RVEMLKYAQT RNNEGLSQSG
AGLFMATGAY DRHLRHLRTC LKTQREQTAD AIAGYFPAGT RINLPPGGLQ LWVELPERLS
SSRVFDAALA ERIVVAPGTL FSNSSRFDHY LRINCGWPYG EAVDTGLRRL GQIIETLMNR
GAGAAAAPLP VRPASPAAAA RPPEARRIQS SSARAA
//
