ID A0A0H4VV01_9BACT Unreviewed; 736 AA.
AC A0A0H4VV01;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Glycosyl hydrolases family 2, TIM barrel domain {ECO:0008006|Google:ProtNLM};
GN ORFNames=TH63_11930 {ECO:0000313|EMBL:AKQ47674.1};
OS Rufibacter radiotolerans.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC Rufibacter.
OX NCBI_TaxID=1379910 {ECO:0000313|EMBL:AKQ47674.1, ECO:0000313|Proteomes:UP000036458};
RN [1] {ECO:0000313|EMBL:AKQ47674.1, ECO:0000313|Proteomes:UP000036458}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DG31D {ECO:0000313|EMBL:AKQ47674.1,
RC ECO:0000313|Proteomes:UP000036458};
RA Kim M.K., Srinivasan S., Lee J.-J.;
RT "Rufibacter sp./DG31D/ whole genome sequencing.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
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DR EMBL; CP010777; AKQ47674.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H4VV01; -.
DR STRING; 1379910.TH63_11930; -.
DR KEGG; ruf:TH63_11930; -.
DR PATRIC; fig|1379910.4.peg.2587; -.
DR Proteomes; UP000036458; Chromosome.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF2; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000036458}.
FT DOMAIN 99..172
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 218..302
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 345..473
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 736 AA; 84005 MW; 788F34DCCCF378A6 CRC64;
MPFLFVFLWT FIAQAQDKKI NPGGMKTTWG EQVTPENAWR QYPRPQLVRT NWLNLNGLWN
YAIVPRNASE PRKFDGKILV PFCAESSLSG VGKIVQPDQK LWYNRTFTVP ASWKNKKVLL
HFDAVDWETT VWVNGKKVGD HKGGSDPFTF DITNALKLGQ QEVVVSVWDP TDTDSQARGK
QVLEPKGIWY TPVTGIWQTV WLEPVDKAYV ASLVPEPNID QNKVVIKNQV TGATGREKLV
VKVLKDNKVI SEKTAAANSP IELSVPNPEL WTPYSPSLYQ LEVQLKDGNK TLDNVKSYFA
MRKVALGKDA MGYERLMLNN QPVFQYGTLD QGWWPDGLLT PPSEAAMRYD MDVLKDMGFN
MLRKHIKVEP SRYYYYADSM GLLVWQDMVT GFKTEDREVQ HVKAEAKEDW ARPAESAKQF
ETEWKSIIDH LKFFPSIAVW VVFNEGWGQY DTRRLVEWTQ KYEPTRVING VSGWTDRGVG
QMNDAHHYPG PGMEPAEQNP GRTIVLGEFG GLGLPLEGHI WNPGMRNWGY RTYKTSDELF
KEYTKLMHNM YPMVHRGLSA AIYTQTTDVE GEVNGLITYD RKKIKIDPEL LRILHKPLYN
TPVKSWAIFP DSEVKPQSLL LTEKKPTVNG FLNKADFAAV NAPVMLKKGD NRWAAQTFTL
AQVPNNLQFR ILAHGDAKVY LNGKLVVNKF INTKRHYDEI NLSEYYSYLK PGDNHLVVEL
MNVGGPAAFD FGLYSF
//
