ID   A0A0H4W2W5_9BACT        Unreviewed;       346 AA.
AC   A0A0H4W2W5;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=N-acetylneuraminate synthase {ECO:0000313|EMBL:AKQ44786.1};
GN   ORFNames=TH63_02745 {ECO:0000313|EMBL:AKQ44786.1};
OS   Rufibacter radiotolerans.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC   Rufibacter.
OX   NCBI_TaxID=1379910 {ECO:0000313|EMBL:AKQ44786.1, ECO:0000313|Proteomes:UP000036458};
RN   [1] {ECO:0000313|EMBL:AKQ44786.1, ECO:0000313|Proteomes:UP000036458}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DG31D {ECO:0000313|EMBL:AKQ44786.1,
RC   ECO:0000313|Proteomes:UP000036458};
RA   Kim M.K., Srinivasan S., Lee J.-J.;
RT   "Rufibacter sp./DG31D/ whole genome sequencing.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP010777; AKQ44786.1; -; Genomic_DNA.
DR   RefSeq; WP_048919583.1; NZ_CP010777.1.
DR   AlphaFoldDB; A0A0H4W2W5; -.
DR   STRING; 1379910.TH63_02745; -.
DR   KEGG; ruf:TH63_02745; -.
DR   PATRIC; fig|1379910.4.peg.591; -.
DR   OrthoDB; 9814210at2; -.
DR   Proteomes; UP000036458; Chromosome.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   CDD; cd11615; SAF_NeuB_like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR   InterPro; IPR006190; AFP_Neu5c_C.
DR   InterPro; IPR036732; AFP_Neu5c_C_sf.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR013132; Neu5Ac_N.
DR   InterPro; IPR020030; Pseudaminic_synth_PseI.
DR   InterPro; IPR013974; SAF.
DR   NCBIfam; TIGR03586; PseI; 1.
DR   PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR   PANTHER; PTHR42966:SF2; PSEUDAMINIC ACID SYNTHASE; 1.
DR   Pfam; PF03102; NeuB; 1.
DR   Pfam; PF08666; SAF; 1.
DR   SMART; SM00858; SAF; 1.
DR   SUPFAM; SSF51269; AFP III-like domain; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   PROSITE; PS50844; AFP_LIKE; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000036458}.
FT   DOMAIN          291..346
FT                   /note="AFP-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50844"
SQ   SEQUENCE   346 AA;  37525 MW;  DFD2CABC54E21E19 CRC64;
     MENIKIGNVT IGKGSTPFII AEMSGNHNQS LDRALAIVNA AADAGAHAIK LQTYTADTMT
     MPGVYTIQDE GSLWKGRELY DLYTEAYTPW EWHKPIFDLA KQRGIIAFSS PFDETAVDFL
     EELGAPLYKI ASFENTDWPL LKKVAATGKP VIMSTGVTSL SDLDESVKIL RDNGCTQLIL
     LKCTSTYPSS PANTNISTIP HMEALFNCPI GLSDHTMGVG VAVAAVALGA CVVEKHFTLS
     RAEGGVDSAF SLEPAELNAL VIETERAWQG LGKVQYGIQK AEEKSKFFKR SIYVSKDVEA
     GDLLTEDNLR VIRPGNGMAP KHLDQVIGKI AKVQIKAGTP LSFDMI
//