ID   A0A0H5CCS5_9PSEU        Unreviewed;       934 AA.
AC   A0A0H5CCS5;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   SubName: Full=Ribonuclease E {ECO:0000313|EMBL:CRK55481.1};
DE            EC=3.1.26.12 {ECO:0000313|EMBL:CRK55481.1};
OS   Alloactinosynnema sp. L-07.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae.
OX   NCBI_TaxID=1653480 {ECO:0000313|EMBL:CRK55481.1, ECO:0000313|Proteomes:UP000076116};
RN   [1] {ECO:0000313|Proteomes:UP000076116}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L-07 {ECO:0000313|Proteomes:UP000076116};
RA   Ramaraj T.;
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR   EMBL; LN850107; CRK55481.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0H5CCS5; -.
DR   STRING; 1653480.gene:80944337; -.
DR   KEGG; alo:CRK55481; -.
DR   Proteomes; UP000076116; Chromosome i.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd04453; S1_RNase_E; 1.
DR   Gene3D; 1.10.10.2480; -; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR019307; RNA-bd_AU-1/RNase_E/G.
DR   InterPro; IPR004659; RNase_E/G.
DR   InterPro; IPR003029; S1_domain.
DR   NCBIfam; TIGR00757; RNaseEG; 1.
DR   PANTHER; PTHR30001; RIBONUCLEASE; 1.
DR   PANTHER; PTHR30001:SF0; RIBONUCLEASE G; 1.
DR   Pfam; PF10150; RNase_E_G; 1.
DR   SMART; SM00316; S1; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS50126; S1; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:CRK55481.1};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000076116};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT   DOMAIN          328..405
FT                   /note="S1 motif"
FT                   /evidence="ECO:0000259|PROSITE:PS50126"
FT   REGION          50..274
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          708..756
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          788..934
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        95..110
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        125..143
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        172..194
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        228..274
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        726..754
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        822..836
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   934 AA;  100949 MW;  6D056FE8C1E01DA3 CRC64;
     MHALAKLLDL SSKDIISALS DLGEEVRGAQ SSVSRDVALK VADALIGTPE AAASTPEAPE
     VAVPEVSVPE VEAEPEPEPE PVRVRRTPPT PVFASASPLF LPPEPVAAPV KAAPVKPVHR
     EEPEDLVEDE VEEPQSAQET PADDDDDSGS RRRRRGRRGR GRGKGAAEDG DTEPKADDES
     TEAEEAEAEE SDDEPSDAAS RRRRRRRRRK GGDEDGDAAA TDDPPNTVVH VREARDEKTE
     AADARNEVRS VRGSTRLEAK RQRRRDGREA GRRRAPILTE SEFLARREAV DRAMIVRENP
     DRTQIAVLED GVLVEHFVTS AGTGSLVGNV YLGRVQNVLP SMEAAFVDIG RGRNAVLYAG
     EVDWDAAGLE GKARKIEQAL STGDSVLVQV TKDPVGHKGA RLTTQISLPG RFLVYVPGGG
     ATGISRKLPE NERRRLKDVL KRIVPEDAGV IIRTASEGIS EEELGRDVRR LQAQWQVIKD
     KSDGTNGVKK SGAPSLLYEE PDLLVKVVRD LFTEDFSALA VQGDTAWETI DSYVRHVAPE
     LLERVRKHVG LKDVFNEHRV DEQLLKALDR KVWLPSGGYL IIDRTEAMTV IDVNTGKFTG
     SGGNLEETVT RNNLESAEEI VRQLRLRDIG GIIVIDFIDM VLESNRDLVL RRLTECLGRD
     RTRHQVAEVT SLGLVQMTRK RVGTGLLEAF STTCEHCKGR GVVVAAEPAT KSPPAPQQQP
     AAPKEHEQGG GRRRNRDRGK EQPAPAEEAP RDDFARSAVQ NIAKATVKVA EHDGHEHDGQ
     VVAAGSEAAQ FESARPAEST DGQSADSIAP AEAAAVSTPV EVDDSDRFEE FGTERTAPAK
     PARSGRSRRA AGRPAGPASD RPAEAIVVAP AQPAEVAAEA PSGPVARRET DSQVNAMANG
     HSAEPTPVAA APRRRARRAA SRPAGPPVNP DQEG
//