ID A0A0H5CTP8_9PSEU Unreviewed; 1092 AA.
AC A0A0H5CTP8;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Serine protease, subtilase family {ECO:0000313|EMBL:CRK61404.1};
DE EC=3.4.21.- {ECO:0000313|EMBL:CRK61404.1};
OS Alloactinosynnema sp. L-07.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae.
OX NCBI_TaxID=1653480 {ECO:0000313|EMBL:CRK61404.1, ECO:0000313|Proteomes:UP000076116};
RN [1] {ECO:0000313|Proteomes:UP000076116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L-07 {ECO:0000313|Proteomes:UP000076116};
RA Ramaraj T.;
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
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DR EMBL; LN850107; CRK61404.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H5CTP8; -.
DR STRING; 1653480.gene:80950302; -.
DR KEGG; alo:CRK61404; -.
DR Proteomes; UP000076116; Chromosome i.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 2.60.40.2310; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF468; SUBTILISIN-LIKE PROTEASE SBT3.18; 1.
DR Pfam; PF17766; fn3_6; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000076116};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..1092
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005217845"
FT DOMAIN 203..636
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 449..517
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 688..765
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT ACT_SITE 211
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 286
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 600
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 1092 AA; 111578 MW; 19BFBD95E0D7D722 CRC64;
MRRSRCARAA VLAMVLPISL VTSGGEAVAA PTLGAEPLTP ADRVTADKSP TSRLAKTDAS
LLGRTDAMLI PVVIKLDYDS LATYAGGRRG LEATSPSVTG KKLKDKTAAQ QKYEAFAAGQ
EQAFKAELAT RAPQAAVGTS LRVVYGGVSA RVPANKISDI LAIPNVVAVQ ADDPNHLLTD
SSPDFIGAPS SYNRLGTTAG AGTGVLYGNL DSGVWPEHPS FADLGNLAAP PGPARVCDYG
DNPLTPANDP FACQRKLVGG AAFTQTYDLV LGDDVFAGTA RDSNGHGTHT ASTSAGNIVN
NVSVLGRAQA PIHGIAPGAW VMEYKVCGPQ GCFPSDTTAA VGQAILDGVD VINYSISGGE
DPFTDPTELA FLDAYAAGLF VAASAGNSGP AAGTSNHLSP WVTTVAASTQ RREFASTLTI
TADNGDTFTA DGASITPGAG PAQIVLASAA PYSNALCTTP APAGLFTGKI VACQRGPGRV
AKGFNVLQGG AAGMVLFNPS RADALTDTHW LPAVHLPDGT SMLAFLGSHT GETARFTAGQ
SRSGQGDVMA AFSSRGPGGN FIKPDVTAPG VQILAGDTPI VESVASGPGG ELFQAIAGTS
MSSPHTAGAA ILLKAINPGW TPGQIKSGLM STATTAVVKE DRSTPADPFD MGSGRIDLRQ
AWAPGITFDE TAANMALLAN DPVNAVHLNV PSVNTNVMPG RLTTVRTAKN VSGLKQKYTV
STTAPAGAKI TVLPKKFSLD PGQSAQLSIT IESQAPAAQF FGQIRLVPDS PQFPALHLPV
AFKTGQSHVT LASECAPTQI AVNATSTCTV TATNTSFTDT TVDLTTRLSN QLKVVSASNA
TVVDKRTVHK TGVTVAGALP GVPSVDAGEL FGYIPLTAFG VTPVPIGDEE IINFNVPAFV
YNGVTYSRVG VDSNGYLVVG GGTADDNNCC SLPTGPSPAR PNNILAPFWT DLDGTGAPGV
YAAVLTDGVN SWLVFEYRVN VFGTTSGRTF QVWIGVNGTQ DITFAYNPAA LPADPGQPFL
VGAENEFGGG DIAAVLPTDD LRVTSTVPVP GASVSYTVTV VGTEPGAGRV TTEMTGAGLP
GTTVVTSVVA IE
//
