ID A0A0I9U1V6_9MYCO Unreviewed; 888 AA.
AC A0A0I9U1V6;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=NAD-dependent epimerase/dehydratase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=ABH38_17920 {ECO:0000313|EMBL:KLO34810.1};
OS Mycobacterium haemophilum.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=29311 {ECO:0000313|EMBL:KLO34810.1, ECO:0000313|Proteomes:UP000036334};
RN [1] {ECO:0000313|EMBL:KLO34810.1, ECO:0000313|Proteomes:UP000036334}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UC1 {ECO:0000313|Proteomes:UP000036334};
RA Greninger A.L., Cunningham G., Miller S.;
RT "Genome sequence of Mycobacterium haemophilum.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLO34810.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LDPR01000021; KLO34810.1; -; Genomic_DNA.
DR RefSeq; WP_047316382.1; NZ_LDPT01000026.1.
DR AlphaFoldDB; A0A0I9U1V6; -.
DR STRING; 1202450.B586_10885; -.
DR PATRIC; fig|29311.18.peg.2468; -.
DR OrthoDB; 9765468at2; -.
DR Proteomes; UP000036334; Unassembled WGS sequence.
DR GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.50.30.10; Phosphohistidine domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR008279; PEP-util_enz_mobile_dom.
DR InterPro; IPR036637; Phosphohistidine_dom_sf.
DR PANTHER; PTHR43615; PHOSPHOENOLPYRUVATE SYNTHASE-RELATED; 1.
DR PANTHER; PTHR43615:SF1; PHOSPHOENOLPYRUVATE SYNTHASE-RELATED; 1.
DR Pfam; PF01370; Epimerase; 1.
DR Pfam; PF00391; PEP-utilizers; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52009; Phosphohistidine domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000036334}.
FT DOMAIN 3..194
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
FT DOMAIN 790..861
FT /note="PEP-utilising enzyme mobile"
FT /evidence="ECO:0000259|Pfam:PF00391"
SQ SEQUENCE 888 AA; 95263 MW; 24D543E3512E3136 CRC64;
MRIAVTGASG VLGRGLAARL LSQGHDVVGI ARRRPESWSS TADFVVADIR DTTAVRRAVM
GAEVVAHCAW ARRPQNQVNI EGARNVLDAM TKTGARRIVF ASSAHVYGAA TAPVTEDDAM
TSVSADGLHQ ARVEEMLAAS GVQWVAVRSA LVVGRGVDNW VRQALALPMI PDIGADRALQ
VIHTDDALRL FVRALLDTEI DSGPVNLAAP GETTLRQIAA TLRRPIVPLG SRLTVLRRPS
FLAELELLQS APLMDTSRLR DEWGFVPAWN AAECIDDFAL AVRGRVSLGE RLVSVPWRLA
NIQDLPAVDV PSEDGVVPRF AGPEGDNGEF DTPIDPRFPT FLATNLSEAL PGPFSPSSAS
VTVRGLRAGG VGIAERLRPG GVIQREIAMR TVAVFAHRLY GGITSGHFMA ETVPFAKPAT
IISNSGFFGP SMASLPIFGA QRPPSESSRV RRQLRTIRNI GVFGGNLIGL SAGSPRDTRD
YIDDVDRLEH LAGVDVTQLD DRRLLSLILL ARDHVVHGWV LASGSFMLCA AFNVLLRGLC
GREAAPPAGP ELVSARSVEA VQRLVCAARR DPNVTRLLAE PGKRLDVLGA QAPEFHAAVL
AELALIGHRG PAEVEMLSTS YADDPELLVR MVAKALSAPA APPPQHARIP LRARPVALLA
ARQLRDREVR RDKMVRAIWV LRGLLREYGR RLTDAGIFGT ADDVFYLLVD ELDELDRLPA
DVAGLVARRR AEQRRLAAIV PPTVFSGSWQ PSTTSSMVLG VGDTLRGVGV CGGRVRGRVR
IVRPETIDDL QPGEILVAEV TDVGYTAAFC YAAGVVTELG GPMSHAAVVA REFGFPCVVD
VQGATRHLPP GALIEVDGSA GEIRVLDMAP EDISPLPVSD QSRHVDRS
//
