ID A0A0J1DKH0_9FIRM Unreviewed; 616 AA.
AC A0A0J1DKH0;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=proton-translocating NAD(P)(+) transhydrogenase {ECO:0000256|ARBA:ARBA00012943};
DE EC=7.1.1.1 {ECO:0000256|ARBA:ARBA00012943};
GN ORFNames=AA931_09440 {ECO:0000313|EMBL:KLU39482.1};
OS Peptococcaceae bacterium 1109.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae.
OX NCBI_TaxID=1655638 {ECO:0000313|EMBL:KLU39482.1, ECO:0000313|Proteomes:UP000036486};
RN [1] {ECO:0000313|EMBL:KLU39482.1, ECO:0000313|Proteomes:UP000036486}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1109 {ECO:0000313|EMBL:KLU39482.1};
RA Town J.R., Dumonceaux T.J.;
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+);
CC Xref=Rhea:RHEA:47992, ChEBI:CHEBI:15378, ChEBI:CHEBI:57540,
CC ChEBI:CHEBI:57783, ChEBI:CHEBI:57945, ChEBI:CHEBI:58349; EC=7.1.1.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000006};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLU39482.1}.
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DR EMBL; LDJB01000003; KLU39482.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J1DKH0; -.
DR STRING; 1655638.AA931_09440; -.
DR PATRIC; fig|1655638.3.peg.1904; -.
DR Proteomes; UP000036486; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1220; TPP-binding domain; 2.
DR InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR InterPro; IPR034300; PNTB-like.
DR PANTHER; PTHR44758; NAD(P) TRANSHYDROGENASE SUBUNIT BETA; 1.
DR PANTHER; PTHR44758:SF1; NAD(P) TRANSHYDROGENASE SUBUNIT BETA; 1.
DR Pfam; PF02233; PNTB; 2.
DR SUPFAM; SSF52467; DHS-like NAD/FAD-binding domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..430
FT /note="NADP transhydrogenase beta-like"
FT /evidence="ECO:0000259|Pfam:PF02233"
FT DOMAIN 447..609
FT /note="NADP transhydrogenase beta-like"
FT /evidence="ECO:0000259|Pfam:PF02233"
SQ SEQUENCE 616 AA; 63998 MW; 61F87EA8494596C8 CRC64;
MLYGIKLMSS PKTAVLGNAL GAGAMLAAIA VALLEAGILT YPLLWAGLGV GTALGWVAAV
KVLMIQMPQM VAALNGLGGG ASALVGLVLA LQGEAVGAFA HFTTGLTIAV GALTFGGSAL
AAAKLHGVVS QRPQELPRHA AVVTVVTVLS LASLFFAGRT AAFVQLILAL VFGVLLTMRV
GGADMPITIS LLNSLSGVAG AIAGFPLKNP LLVAVGGIVG ASGFILTQIM CRAMNRSLLS
ILTGRTTVTG TPSRESGLEA PTQAASACQW EQALAEAERV AIIPGYGMAV AQAQLQVKEL
IDLLEAGHKE VKVGIHPVAG RMPGHMNVLL AEVDVPYEKL HDMEAINEFL PGADLAIVVG
ANDVVNPAAM AQPGTPIYGM PIIRADLAKH VMVLNYDTQP GYAGVPNSLY EEPHVSLLLG
DAKETLEKVL GFLRQPQKEV AGGRPSAEAG KFLSQAEQVI IVPGYGMALA AAQHQVRELV
DVLQGRGIQV KIGIHPVAGR MPGHMNVLLA EVDIPYDMLY TLDEINPEFS STDVVLVVGA
NDVVNPAAQT AEGTPIYGMP ILSVSDARHV VVCNLDRSPG YAGVPNALYN MPHCLFVEGD
ASQTLREIIS VLTEQG
//
