ID A0A0J6NQL4_9NEIS Unreviewed; 386 AA.
AC A0A0J6NQL4;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Hemolysin D {ECO:0000313|EMBL:KMN83057.1};
GN ORFNames=VK98_06140 {ECO:0000313|EMBL:KMN83057.1};
OS Chromobacterium sp. LK11.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
OC Chromobacteriaceae; Chromobacterium.
OX NCBI_TaxID=1628212 {ECO:0000313|EMBL:KMN83057.1, ECO:0000313|Proteomes:UP000036114};
RN [1] {ECO:0000313|EMBL:KMN83057.1, ECO:0000313|Proteomes:UP000036114}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LK11 {ECO:0000313|EMBL:KMN83057.1,
RC ECO:0000313|Proteomes:UP000036114};
RA Chan X.Y.;
RT "Draft genome of Chromobacterium aquaticum LK11.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMN83057.1}.
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DR EMBL; LDUR01000009; KMN83057.1; -; Genomic_DNA.
DR RefSeq; WP_048413165.1; NZ_LDUR01000009.1.
DR AlphaFoldDB; A0A0J6NQL4; -.
DR STRING; 1628212.VK98_06140; -.
DR PATRIC; fig|1628212.3.peg.4730; -.
DR OrthoDB; 9811754at2; -.
DR Proteomes; UP000036114; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR005694; MFP_proteobact.
DR NCBIfam; TIGR00998; 8a0101; 1.
DR PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR PANTHER; PTHR30386:SF19; MULTIDRUG EXPORT PROTEIN EMRA-RELATED; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000036114};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 27..338
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT DOMAIN 150..280
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 386 AA; 41283 MW; 3BDCCA3C26185257 CRC64;
MDKKTKTAQG RKRNLIVATT LFAAIAIGYG AYWALVLSHQ ESTDDAYVSG HLVQVTPEVG
GTVAKVLVDD TQHVKAGQLL VSLDKNDAQL NFDRARNEFA QVVRQTRQLM NNTQQLAAQV
TLRETELART DSDLKRRKQL AGTDALSAEE LSHANDAVAA AKAALDAARE QQKASAALLG
KDALAQQPAV KAAASRLKEA WLALQRTEIK APLDGAVARR NVQVGQRLAA GTPLMSVIPL
QNLWVDANFK EGQLAKIRIG QPVELKSDLY GGKIVYHGKV VGLSAGTGSA FSLLPAQNAT
GNWIKVVQRV PVRIQLDPKD LQSHPLRVGL SMDAVVDTSG TDGKAVAEAQ PFVAHQDVSG
QLPDLKQADE LVRTLLAANA GEGKAE
//
