ID A0A0J7KIQ8_LASNI Unreviewed; 1536 AA.
AC A0A0J7KIQ8;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Alsin {ECO:0000313|EMBL:KMQ90323.1};
GN ORFNames=RF55_9935 {ECO:0000313|EMBL:KMQ90323.1};
OS Lasius niger (Black garden ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Lasius; Lasius.
OX NCBI_TaxID=67767 {ECO:0000313|EMBL:KMQ90323.1, ECO:0000313|Proteomes:UP000036403};
RN [1] {ECO:0000313|EMBL:KMQ90323.1, ECO:0000313|Proteomes:UP000036403}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole {ECO:0000313|EMBL:KMQ90323.1};
RA Konorov E.A., Nikitin M.A., Kirill M.V., Chang P.;
RT "Lasius niger genome sequencing.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMQ90323.1}.
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DR EMBL; LBMM01006796; KMQ90323.1; -; Genomic_DNA.
DR STRING; 67767.A0A0J7KIQ8; -.
DR PaxDb; 67767-A0A0J7KIQ8; -.
DR OrthoDB; 3740287at2759; -.
DR Proteomes; UP000036403; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR CDD; cd13269; PH_alsin; 1.
DR Gene3D; 2.20.110.10; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 4.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 2.
DR Gene3D; 1.20.1050.80; VPS9 domain; 1.
DR InterPro; IPR003409; MORN.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR InterPro; IPR003123; VPS9.
DR InterPro; IPR037191; VPS9_dom_sf.
DR PANTHER; PTHR46089; ALSIN HOMOLOG; 1.
DR PANTHER; PTHR46089:SF2; ALSIN HOMOLOG; 1.
DR Pfam; PF02493; MORN; 8.
DR Pfam; PF13540; RCC1_2; 1.
DR Pfam; PF02204; VPS9; 1.
DR SMART; SM00698; MORN; 8.
DR SUPFAM; SSF82185; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 2.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 2.
DR SUPFAM; SSF109993; VPS9 domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50012; RCC1_3; 2.
DR PROSITE; PS51205; VPS9; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000036403}.
FT REPEAT 441..492
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 493..546
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT DOMAIN 868..902
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 1390..1536
FT /note="VPS9"
FT /evidence="ECO:0000259|PROSITE:PS51205"
FT REGION 365..390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1536 AA; 172743 MW; 28539FF21EC6C99A CRC64;
MDKHMYLWRG ADKLSFAFGD KPNGVICKLV TIKDHIFVAT TTNNLYHGEV SFPESTCPML
IFKRAQFDVV IDIASNSEHL FIVNTKGHVL KVNPQDMSVI DLIILKEEVK YCSHGYKEEN
EVVKVKSIAV SDHATLFVTE NGQLWASGNQ PQIDISSIEP KKVRFFEGRT VSEVACGSNF
NVVTVRKTTK PMKEDTDSEN ELEEEVFINS CPQCLNNVML SPGSVTSSDT CLTGLHAQQF
SEDRSTNSIS ALSTASKEHI SLPEIDKKEL SGIIENGGEC PNNLTDSDKD EKRNVIFINT
ETARQFLTRQ LSWVSSYGSA KEDIPMESVD RSTRLIKQNV SNMANLVYEG VKNVGGKVVT
LSRHMSGSSD INEGKADSNE NLEEQGDSYT KPTATSLALS LRCEEFPWSS STGSSEHELS
QQGLNERINT LSRTGSNILA TELWTWGDVQ YGQLGTGDII KRPRPVLVAK LSHTGIRKIS
CGAFHVLALT LDGRVFAWGR NNFKQVTLHT TVDQSAPQLF TTKLSSTERA IDMAAGNFHS
LIMMHHGLYF MGQSSKVGDM FQFDIQGKDE ANSPREIFSS GQYSCCSMIN EPAINMSEDL
INDQIFLEEM LIVYQNLIKP FQKKSGGIQE ANVYETLCRC YAELMHFSVL NVISLWDYFN
HIGEAYEVAI VANIEEFTTV YKYYLNAICD VISLGGFMHI AKFIEVPQVV SNLFINNLKS
SDVKRNNNEI VITMALQHPL CKLNRYKNMI HSLIKSNGTK MGVERLQEAL IKWEQVHDEQ
EKRQKEADAT KLFWESSGKL GELLRSPNRR LIRESKTYPL SILNSGRFSS HWFVLLTDIF
IHVTGTTHTV HPLRTLWVEP LPDSENIQNA ISIVTPEDNF VLYTPTPSER NEWLHALQNT
IKCSLQRVIG NVPPLARSSS FSFTKHNVFK DATYTGRWLN GKPHGSGKLE WSDGRTYVGQ
FHKGVLHGTG KMEIPMQGVY EGQWKDGQQN GYGTMKYING DFYEGYFKDG LPHGHGVKKE
GHFMASVASV YIGEWAAGVK QGYGIMDDIM TGEKYLGSWS NGLKHGNGLI VTLDGIYYEG
AFTQDVLTGH GVMVFEDGTH YEGEFKSAGI FCGKGTLTFR SGDRLEGNLN GAWNEGVKVI
ATLHMNKASG TTQTNSKPAS FGKLCVSADQ KWKAIFKQCY QQLGISESVT KSSSYNEKSV
ETQRVWQNVA SIITKSHQKT LQRKKLSANT ASDMKERNSE TIDQLDKIPC FGRDKLTSQT
YNEVHKYLMK AFESPHHPLG ALLTEVAAVY TATYGGVRVH PLLLSHAVSE LHSITTRIYE
IVLLLFPALP RCGKEYVLET DGEEEQVISA AAILHPILLP RVHSALFVLY ALHNKKEDDA
YWERLMKWNK QPDITLMAFL EIDQKFWKTT NVMNIAENSL PYQHEPYFSD AIETLQQLKT
TFSPLEKLLV IRNTFEQMTQ AVQKQLGSTY LWTMDELFPV FSFVVVRASV LQLGSEIHFI
EDFMEPYLQN GELGIMFTTL KACYYQILQE KTNMGD
//
