ID A0A0J8QJM3_COCIT Unreviewed; 157 AA.
AC A0A0J8QJM3;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=D-lactate dehydrogenase {ECO:0000313|EMBL:KMU72609.1};
GN ORFNames=CISG_09799 {ECO:0000313|EMBL:KMU72609.1};
OS Coccidioides immitis RMSCC 3703.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=454286 {ECO:0000313|EMBL:KMU72609.1, ECO:0000313|Proteomes:UP000054559};
RN [1] {ECO:0000313|Proteomes:UP000054559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 3703 {ECO:0000313|Proteomes:UP000054559};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; DS268224; KMU72609.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J8QJM3; -.
DR STRING; 454286.A0A0J8QJM3; -.
DR Proteomes; UP000054559; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR Gene3D; 3.30.70.2740; -; 1.
DR InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR PANTHER; PTHR11748; D-LACTATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11748:SF116; D-LACTATE DEHYDROGENASE (CYTOCHROME) (AFU_ORTHOLOGUE AFUA_7G02560); 1.
DR Pfam; PF02913; FAD-oxidase_C; 1.
DR SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054559}.
FT DOMAIN 2..143
FT /note="FAD-binding oxidoreductase/transferase type 4 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF02913"
SQ SEQUENCE 157 AA; 17667 MW; 9FB9E3CD5A9AF827 CRC64;
MQELWSARKE ALWSVMAMKR DQNDHVWTTD VAVPISRLPD IIEQTKEDIT KNGLLGGICG
HVGDGNFHAI LLFNDSERNV AEGVVHRMVK RAVEMEGTVT GEHGVGLIKR DYLPHELGDS
AVDTMRKIKQ ALDPLCLLNC DKVVRMEPPK QGEIKKW
//
