ID A0A0K0JQX8_BRUMA Unreviewed; 440 AA.
AC A0A0K0JQX8;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Bm7099 {ECO:0000313|EMBL:CTP81133.1};
DE SubName: Full=Histidine acid phosphatase family protein {ECO:0000313|WBParaSite:Bm7099.1};
GN Name=bma-acp-7 {ECO:0000313|WormBase:Bm7099};
GN ORFNames=Bm7099 {ECO:0000313|EMBL:CTP81133.1,
GN ECO:0000313|WBParaSite:Bm7099.1, ECO:0000313|WormBase:Bm7099},
GN BM_Bm7099 {ECO:0000313|EMBL:CTP81133.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CTP81133.1};
RN [1] {ECO:0000313|EMBL:CTP81133.1, ECO:0000313|Proteomes:UP000006672}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CTP81133.1,
RC ECO:0000313|Proteomes:UP000006672};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CTP81133.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CTP81133.1};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:Bm7099.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2019) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000032};
CC -!- SIMILARITY: Belongs to the histidine acid phosphatase family.
CC {ECO:0000256|ARBA:ARBA00005375}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LN856924; CTP81133.1; -; Genomic_DNA.
DR RefSeq; XP_001898022.1; XM_001897987.1.
DR STRING; 6279.A0A0K0JQX8; -.
DR EnsemblMetazoa; Bm7099.1; Bm7099.1; WBGene00227360.
DR GeneID; 6101466; -.
DR KEGG; bmy:BM_BM7099; -.
DR WBParaSite; Bm7099.1; Bm7099.1; WBGene00227360.
DR CTD; 6101466; -.
DR WormBase; Bm7099; BM28384; WBGene00227360; Bma-acp-7.
DR OMA; EWNHALE; -.
DR OrthoDB; 2875604at2759; -.
DR Proteomes; UP000006672; Unassembled WGS sequence.
DR CDD; cd07061; HP_HAP_like; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR000560; His_Pase_clade-2.
DR InterPro; IPR029033; His_PPase_superfam.
DR PANTHER; PTHR11567:SF29; ACID PHOSPHATASE FAMILY; 1.
DR PANTHER; PTHR11567; ACID PHOSPHATASE-RELATED; 1.
DR Pfam; PF00328; His_Phos_2; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006672};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..440
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013455919"
SQ SEQUENCE 440 AA; 50377 MW; D8EC403AC5ACEF14 CRC64;
MLIIWYVAIY CIVLSLEQNI PLVLETAAID ENVKLVIFGM RHGNCHPGKF LNKNSRTWGF
EGVHELTQFG KREGFAFGKE LREFVGPFVA NNYMQHEVAF YTSSTNRCQM TLQVVMAGFY
PPDTFAEWNH ALEWSPVPYT IDDSMLQMHS IPNCNTTQRA WEPIIYDNLP ELVHTTVANA
KLLDYIAKHT GWNRSIESAS DLADNIVKMN LYNTSLPGWI EKPTLEEFDK QSLKEAIMTL
LEKHPLTCVN YEPCRDIMGG IWLNHILTAL RNAVDGQQTR KFIGYVSHLE VTLSVMKLLR
INQTYLETTA GFLLEYRDKP NKSIRLLFHE ASTIDRHIIR QAKYLKELKE LSDSNHWIPF
ELFYQLVKNK AIANWEEACG EKITQCVATG SGSKMPLQRT VADSNNGDTL TDNRTTSSAP
FTISLYNIVI HLLVTLWFVS
//
