ID A0A0K2LWC8_9NOST Unreviewed; 616 AA.
AC A0A0K2LWC8;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Cl-channel voltage-gated family protein {ECO:0000313|EMBL:ALB40115.1};
GN ORFNames=AA650_06235 {ECO:0000313|EMBL:ALB40115.1};
OS Anabaena sp. WA102.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Anabaena.
OX NCBI_TaxID=1647413 {ECO:0000313|EMBL:ALB40115.1, ECO:0000313|Proteomes:UP000056652};
RN [1] {ECO:0000313|EMBL:ALB40115.1, ECO:0000313|Proteomes:UP000056652}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WA102 {ECO:0000313|EMBL:ALB40115.1,
RC ECO:0000313|Proteomes:UP000056652};
RA Brown N.M.;
RT "The finished genome of an anatoxin-a-producing Anabaena isolate reveals
RT extensive genome rearrangement.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP011456; ALB40115.1; -; Genomic_DNA.
DR RefSeq; WP_053538387.1; NZ_CP011456.1.
DR AlphaFoldDB; A0A0K2LWC8; -.
DR STRING; 1647413.AA650_06235; -.
DR KEGG; awa:AA650_06235; -.
DR PATRIC; fig|1647413.5.peg.1478; -.
DR OrthoDB; 9812438at2; -.
DR Proteomes; UP000056652; Chromosome.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd02205; CBS_pair_SF; 1.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 310..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 404..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 459..518
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 616 AA; 65933 MW; B42C6BA9C861C371 CRC64;
MRFTQLINRF QASPETVVLF LAVLIGSSTG MGIVTFHYLI QLINNFMLEN LMGQIGIWGA
WTLAAVPILG GIIVGLMRWR TQDFGPGLSS LIAVSQGKEA KKPLRPVTKM IAAAVSLGSG
ASLGPEGPSV EIGTNFGVLL SDVLQVSQER QRLLLGAGAA AGLAAGFNAP IAGVFFALEV
VMGSTYFATS AVSVVLLAAV VAALIAQIGL GSQPAFALPA YQVRSYLELP LYLGLGLGAS
LISLTYTESI RLAKAIFAGN FSGLTLLGKI PQSIQPIFGG VILGLVGWQY PQILGIGYGT
VEAILQDEDF SLNLLLILLV LKLLMTAVSS GSGFVGGLFA PAMFLGASFG SAYAKFLALI
IPGIGEYMAA PPAYAMVGMA AVLAGSVRAP LTAILMLFEL TRDYRIVLPL MAAVGLSVWL
VELIKPTVDA NANLQQIGLP ELKDEKVELW QQMLVADAMY TCPKKLSATL GVLETAVVMT
RERIRSALII DDDTGKLVGI LSLEDIKRTF FICQNLPNSL PEIQEYLSSQ KLIDICTTDI
LYAWDDEPVS EALDRMALRG LHQLPVVAKD NPDFILGLLE REQIELTCNL TAITKILHQY
SPVIPTAEYI EEIGNW
//
