ID A0A0K8JI30_9FIRM Unreviewed; 474 AA.
AC A0A0K8JI30;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Hydroxyacid dehydrogenase {ECO:0008006|Google:ProtNLM};
GN ORFNames=P22_3388 {ECO:0000313|EMBL:CUH97261.1};
OS Propionispora sp. 2/2-37.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC Propionispora.
OX NCBI_TaxID=1677858 {ECO:0000313|EMBL:CUH97261.1, ECO:0000313|Proteomes:UP000041641};
RN [1] {ECO:0000313|EMBL:CUH97261.1, ECO:0000313|Proteomes:UP000041641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2/2 {ECO:0000313|EMBL:CUH97261.1};
RA Jackson K.R., Lunt B.L., Fisher J.N.B., Gardner A.V., Bailey M.E.,
RA Deus L.M., Earl A.S., Gibby P.D., Hartmann K.A., Liu J.E., Manci A.M.,
RA Nielsen D.A., Solomon M.B., Breakwell D.P., Burnett S.H., Grose J.H.;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the four-carbon acid sugar kinase family.
CC {ECO:0000256|ARBA:ARBA00005715}.
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DR EMBL; CYSP01000017; CUH97261.1; -; Genomic_DNA.
DR RefSeq; WP_054261371.1; NZ_CYSP01000017.1.
DR AlphaFoldDB; A0A0K8JI30; -.
DR STRING; 1677858.P22_3388; -.
DR OrthoDB; 153193at2; -.
DR Proteomes; UP000041641; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.980.20; Four-carbon acid sugar kinase, nucleotide binding domain; 1.
DR Gene3D; 3.40.50.10840; Putative sugar-binding, N-terminal domain; 1.
DR InterPro; IPR010737; 4-carb_acid_sugar_kinase_N.
DR InterPro; IPR037051; 4-carb_acid_sugar_kinase_N_sf.
DR InterPro; IPR031475; NBD_C.
DR InterPro; IPR042213; NBD_C_sf.
DR PANTHER; PTHR43060; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR43060:SF17; L-THREONATE DEHYDROGENASE; 1.
DR Pfam; PF17042; NBD_C; 1.
DR Pfam; PF07005; SBD_N; 1.
DR SUPFAM; SSF142764; YgbK-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000041641};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 36..276
FT /note="Four-carbon acid sugar kinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF07005"
FT DOMAIN 302..462
FT /note="Four-carbon acid sugar kinase nucleotide binding"
FT /evidence="ECO:0000259|Pfam:PF17042"
SQ SEQUENCE 474 AA; 52518 MW; 7797627DCA51AF7A CRC64;
MKKLAKKSVF SKIKEIDVGI VDTELEEALS NLNKKIIVLD DDPTGIQTVH DISVYTDWST
ESIAAGFAEE QPMFFILTNS RALTVEQTRM VHKEIAENIV AESKKCGKNF IIISRGDSTL
RGHYPLETQI LKETLEAASA IRFDGEVLIP FFKEGGRFTI DNVHYVQESQ TLVPVGETEF
AKDKTFSFAA SELGEYIEEK TEGSYKAADT TYITLEDLRN LKIPEISRQL LAVKEFNKVI
VNAVDYVDVK IFTIALLQVI AQGKNFMFRT AAAFTKVIGG LNDQELLNKA DLVAKGNKNG
GLIIVGSHVE KTTHQLAELQ KCTDIRFFEF NQGLVVEPEQ LETAIQSIIV ETEKYLKRGE
TVTIFTGRKR LDAGTEEESL RLSVKISAAL TAIVQRLSVQ PSFLIAKGGI TSSDVGTKGL
NVKKARVMGQ VKPGVPVWLT GQEAKFANMP YIIFPGNVGG IMTLREVVEM LNNQ
//
