ID   A0A0K8P5U6_IDESA        Unreviewed;       735 AA.
AC   A0A0K8P5U6;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Prolyl endopeptidase {ECO:0000313|EMBL:GAP37961.1};
DE            EC=3.4.21.26 {ECO:0000313|EMBL:GAP37961.1};
GN   ORFNames=ISF6_4155 {ECO:0000313|EMBL:GAP37961.1};
OS   Ideonella sakaiensis (strain NBRC 110686 / TISTR 2288 / 201-F6).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Sphaerotilaceae; Piscinibacter.
OX   NCBI_TaxID=1547922 {ECO:0000313|EMBL:GAP37961.1, ECO:0000313|Proteomes:UP000037660};
RN   [1] {ECO:0000313|Proteomes:UP000037660}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 110686 / TISTR 2288 / 201-F6
RC   {ECO:0000313|Proteomes:UP000037660};
RA   Yoshida S., Hiraga K., Takehana T., Taniguchi I., Yamaji H., Maeda Y.,
RA   Toyohara K., Miyamoto K., Kimura Y., Oda K.;
RT   "Discovery of a poly(ethylene terephthalate assimilation.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:GAP37961.1, ECO:0000313|Proteomes:UP000037660}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 110686 / TISTR 2288 / 201-F6
RC   {ECO:0000313|Proteomes:UP000037660};
RX   PubMed=26965627; DOI=10.1126/science.aad6359;
RA   Yoshida S., Hiraga K., Takehana T., Taniguchi I., Yamaji H., Maeda Y.,
RA   Toyohara K., Miyamoto K., Kimura Y., Oda K.;
RT   "A bacterium that degrades and assimilates poly(ethylene terephthalate).";
RL   Science 351:1196-1199(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAP37961.1}.
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DR   EMBL; BBYR01000064; GAP37961.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0K8P5U6; -.
DR   STRING; 1547922.ISF6_4155; -.
DR   Proteomes; UP000037660; Unassembled WGS sequence.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 2.130.10.120; Prolyl oligopeptidase, N-terminal domain; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR023302; Pept_S9A_N.
DR   InterPro; IPR001375; Peptidase_S9.
DR   InterPro; IPR002470; Peptidase_S9A.
DR   InterPro; IPR006311; TAT_signal.
DR   PANTHER; PTHR42881; PROLYL ENDOPEPTIDASE; 1.
DR   PANTHER; PTHR42881:SF13; PROLYL ENDOPEPTIDASE; 1.
DR   Pfam; PF00326; Peptidase_S9; 1.
DR   Pfam; PF02897; Peptidase_S9_N; 1.
DR   PRINTS; PR00862; PROLIGOPTASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF50993; Peptidase/esterase 'gauge' domain; 1.
DR   PROSITE; PS51318; TAT; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:GAP37961.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037660};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           30..735
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5005513742"
FT   DOMAIN          48..448
FT                   /note="Peptidase S9A N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02897"
FT   DOMAIN          526..729
FT                   /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00326"
FT   REGION          29..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   735 AA;  80825 MW;  C6ACCEE136B4611C CRC64;
     MSDSLPSPRR RALAAAGLAS LLGPLPRTAM SQAASAPATP PPAAPVPDDP FRWLEDVQGD
     KSLAWVRERN AASQAVLGTR PEFEPIRREL LEVLNAKDRI PAVTRRGAWL YNLWQDEQHK
     RGLWRRTTLA EYRKPQPAWE TVLDLDALGA AEKENWVWGG AVALAPEYRR CLVALSRGGA
     DATVVREFDT VTKRFVDGGF TLPEAKSEVD WIDADTVYVA TDFGAGSLTD SGYPRVIKRW
     KRGTPLSDAQ TVFEGQASDV SVSVGIDDTP GHERTQFYRA TDFYNRKTFL LPHGAEPKAM
     QPLDVPDDAV VGFMRDTLLL ELRSDWTVGG TRHPAGSLLA ADAAAYLKGE RRFQVLFTPT
     PTRSLSGRIQ TRDHLVLNLI DNVASTLAMW HKTPQGFVSV PIEAPTPGSL GLASLHDPRV
     PKDPLANHYL LTYTDFLTPD TLYLGDTTAA PQAPRERLKQ RQPLFDATGM RAEQRFARSK
     DGTRVPYFVV WPKGAQADGR TPTLLYGYGG FKISLKPWYS GGFGRAWLSR GGALVIANIR
     GGGEFGPAWH QAAVKANKQR SYDDFIAVAE DLVAAKVTSP RHLGIMGGSN GGLLVGATMV
     QRPDLFNAVV CQVPLLDMRR YNVLLAGASW MAEYGNPDLP AEWAWISGYS PYQNVKPGVK
     YPKVLFTTST RDDRVHPGHA RKMAARMLAQ GHEVLYYENI EGGHGGAADN EQRAYLQSLE
     YAYLWQQLGP AGRGG
//