ID A0A0K8PA12_9CHLR Unreviewed; 626 AA.
AC A0A0K8PA12;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein {ECO:0000313|EMBL:GAP39349.1};
GN ORFNames=ATC1_11277 {ECO:0000313|EMBL:GAP39349.1};
OS Flexilinea flocculi.
OC Bacteria; Chloroflexota; Anaerolineae; Anaerolineales; Anaerolineaceae;
OC Flexilinea.
OX NCBI_TaxID=1678840 {ECO:0000313|EMBL:GAP39349.1};
RN [1] {ECO:0000313|EMBL:GAP39349.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TC1 {ECO:0000313|EMBL:GAP39349.1};
RA Matsuura N., Tourlousse D.M., Sun L., Toyonaga M., Kuroda K., Ohashi A.,
RA Cruz R., Yamaguchi T., Sekiguchi Y.;
RT "Draft Genome Sequence of Anaerolineae Strain TC1, a Novel Isolate from a
RT Methanogenic Wastewater Treatment System.";
RL Genome Announc. 3:e01104-15(2015).
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
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DR EMBL; DF968179; GAP39349.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0K8PA12; -.
DR STRING; 1678840.ATC1_11277; -.
DR PATRIC; fig|1678840.3.peg.327; -.
DR OrthoDB; 9761899at2; -.
DR Proteomes; UP000053370; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR CDD; cd02980; TRX_Fd_family; 1.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 6.10.250.1450; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR001949; NADH-UbQ_OxRdtase_51kDa_CS.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR PANTHER; PTHR43578:SF3; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR Pfam; PF01257; 2Fe-2S_thioredx; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF00037; Fer4; 2.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
DR PROSITE; PS00645; COMPLEX1_51K_2; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053370}.
FT DOMAIN 569..598
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 599..626
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 626 AA; 68178 MW; CCE19DC95A7302DA CRC64;
MNRINSYSEL LSTCESLKPL LHSRLNTGIR PDEKKLILIC GGTGCHASES DKILAKFESL
IDEKNLQNVV AASKTGCFGF CAKGPIVKIF PDDVFYVQVK IEDAEEIIDQ HIVNNQVVKR
LLFEDPISKQ RIPTQHEIPF YKNQKRIALR NCGLINPEKI EEYIATGGYQ ALGRAVAEMT
PEEVIEEMKR SGLRGRGGAG FPTGKKWEFG RSYKSDEKFV ICNADEGDPG AFMDRSILEG
DSHSVLEGMA LAGYAIGANK GYVYIRAEYP LAVERLKIAI KQAHDAGVLG KNILGSGFDF
EIDIRLGAGA FVCGEETALI NSIQGKRGEP HTKPPFPAQS GLWDKPTVVN NVETLANVPI
VMLKGADWFN TIGSKTSKGT KVFALAGQIN NVGLVEVPMG TTLREIIYDT GGGIKGNLDF
KAAQTGGPSG GCIPKQFLDT PIDYESLASI GSMMGSGGMI IMSEKDCMVN IAKFYLEFTV
EESCGRCVPC RIGTKRLHEI LSSITEGRGT EADLAELQSL AKVITDTALC GLGQTAPNPV
LSTLKYFMDE YEAHVKEKRC PAGVCKSLLN FEILPDKCIG CTTCARNCPV NCISGVVKQP
HVIDQSRCIK CGTCYSKCKF QAIIRH
//
